Parathyroid Hormone Related Peptide N-Terminal (PTHrP), Plasma

PTH-Related Peptide; Parathyroid Related Polypeptide; Parathyroid Related Protein; PTH Related Protein

Plasma (EDTA)

You must specify "Mayo" or "N-Terminal" to order this test.
Please note that PTHrP analysis as a C-Terminal assay is available at Quest: Parathyroid Hormone Related Protein C-Terminal (PTHrP), Plasma.

Aiding in the evaluation of patients with hypercalcemia of unknown origin.
Aiding in the evaluation of patients with suspected humoral hypercalcemia of malignancy.
The test should not be used to exclude cancer or screen tumor patients for humoral hypercalcemia of malignancy.

Two PTHrP assays are offered, one targeting the N-terminal peptides (Parathyroid Hormone Related Peptide N-Terminal (PTHrP), Plasma) and the other targeting the C-terminal peptides (Parathyroid Hormone Related Protein C-Terminal (PTHrP), Plasma). The C-terminal fragment may accumulate in patients with renal impairment and the N-terminal fragment clearance is not affected by renal impairment. To avoid detection of excess C-terminal fragments in renal impairment choose the N-terminal assay.
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