Neuromyelitis Optica Spectrum Profile, CSF; test site LHSC

Anti Myelin Oligodendrocyte; Glycoprotein and Anti Aquaporin4 IgG; Anti AQP4 antibody; Anti NMO antibody; Anti MOG antibody; NMOSDCSF

Anti-AQP4; Anti-MOG

CSF

Important Note: Neuromyelitis Optica testing is available at multiple testing labs. Non-interfaced clients should specify the Test ID NMOSP CSF when ordering this test. Not doing so will cause processing delays while ICL ascertains which test you are requesting.

This test can be used to help distinguish between Multiple Sclerosis (MS) and Neuromyelitis Optica Spectrum Disorders (NMOSD).

A single autoantibody test is not diagnostic and should not be used to determine course of treatment. The test result must be evaluated with consideration of clinical presentation, patient history and other laboratory tests.

Testing for AQP4 and MOG antibodies may be more sensitive in serum than in CSF. CSF testing should only be considered in patients receiving acute immunotherapy such as plasma exchange, and should be accompanied by a serum sample.

Serum testing is performed at an additional fee, and can be ordered using Test ID NMOSP S. See the web listing for Neuromyelitis Spectrum Profile, Serum.