Comprehensive Autoimmune Encephalitis Panel (LHSC), CSF
Test Overview
Clinical Utility
A clinical diagnosis should not be made solely based on a neural antibody result; results should be interpreted in the context of the patients clinical presentation and other ancillary test findings to ensure accurate diagnosis.
Method
Various
Method Description
Cell-based assay (CBA) and tissue indirect immunofluorescence (TIIF) assay for autoimmune encephalitis antibodies (reported based on CBA).
Immunoblot and tissue indirect immunofluorescence (TIIF) assay for paraneoplastic antibodies (reported based on immunoblot).
ELISA and immunoblot for Anti-GAD65.
Each sample will also be screened for neural antibodies based on research use-only TIIF.
Result Included
Autoimmune Encephalitis Antibodies:; Anti-NMDAR; Anti-LGI1; Anti-CASPR2; Anti-AMPAR1/R2; Anti-GABARB1/B2; Anti-DPPX
Paraneoplastic Antibodies:Anti-Hu (ANNA-1); Anti-Ri (ANNA-2); Anti-Yo (PCA-1); Anti-Amphiphysin; Anti-CV2 (CRMP5); Anti-Ma2/Ta (PNMA2); Anti-Tr (DNER); Anti-Zic4; Anti-Recoverin; Anti-Titin; Anti-SOX1;
Other Antibody: Anti-GAD65
Research-only Neural Antibodies:; Anti-GFAP; Anti-mGluR1; Anti-NIF; Anti-Neurochondrin; ANNA-3; PCA-2/Anti-MAP1B; Anti-AP3B2; Anti-PDE10A; Anti-KLHL11; Anti-ITPR1; Anti-GRAF
Aliases/Synonyms
Paraneoplastic antibodies
Specimen
Specimen Type
CSFParaneoplastic Antibodies included in this Panel may be ordered on their own: Paraneoplastic Antibodies Expanded Panel (LHSC), CSF
Volume
Sample Volume
1 mL
Collection & Handling
Handling Information
Store and send cold or frozen.
Stability
| Refrigerated | Frozen |
|---|---|
| 14 days | 30 days |
Performance & Interpretation
Turnaround Time
9 days
Results
-
VariousNegative
-
Anti-GAD65 ELISAIU/mL≤ 5
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| AEP CSF | Anti-AMPAR1/R2 CBA,CSF | 63469 | |
| Anti-CASPR2 CBA,CSF | 63470 | ||
| Anti-DPPX CBA,CSF | 63471 | ||
| Anti-GABARB1/B2 CBA,CSF | 63472 | ||
| Anti-LGI1 CBA,CSF | 63473 | ||
| Anti-NMDAR CBA,CSF | 63474 | ||
| Anti-Amphiphysin Immunoblot, CSF | 63475 | ||
| Anti-CV2 Immunoblot, CSF | 63476 | ||
| Anti-GAD65 Immunoblot, CSF | 63477 | ||
| Anti-Hu Immunoblot, CSF | 63478 | ||
| Anti-Ma2:Ta Immunoblot, CSF | 63479 | ||
| Anti-SOX1 Immunoblot, CSF | 63480 | ||
| Anti-Recoverin Immunoblot, CSF | 63481 | ||
| Anti-Ri Immunoblot, CSF | 63482 | ||
| Anti-Titin Immunoblot, CSF | 63483 | ||
| Anti-Tr (DNER) Immunoblot, CSF | 63484 | ||
| Anti-Yo Immunoblot, CSF | 63485 | ||
| Anti-Zic4 Immunoblot, CSF | 63486 | ||
| Antibody Result, CSF | 63488 | ||
| Research Based Antibody Screen,TIIF,CSF | 63489 |
Test Version
Last Updated
2026-03-17