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Lactate Dehydrogenase (LD) Isoenzymes, Serum (Until 31 January, 2024)

Test ID: LDISO

Test

Aliases/Synonyms

Lactate Dehydrogenase (LDH) Isoenzymes

Method

Electrophoresis Densitometry (LDI) & Photometric Rate (LD)

Report Includes

Lactate Dehydrogenase (LD); LD Iso - I (Heart); LD Iso - II; LD Iso - III; LD Iso - IV; LD Iso - V (Liver)

Specimens

Serum
You must submit a completed Biochemical Genetics Patient Information form with the specimen. The requisition is mandatory as the information you provide is required in order to issue an interpretive report.

Test Location

Mayo Clinical Labs, Minnesota USA

Test Version

19-Jan-2024

Specimen

Specimens

Serum
You must submit a completed Biochemical Genetics Patient Information form with the specimen. The requisition is mandatory as the information you provide is required in order to issue an interpretive report.

Sample Volume

2 mL

Minimum Volume

0.75 mL

Specimen Comment

Gel-separator tube preferred.

Collection & Handling

Collection Instructions

Avoid hemolysis.

Handling Information

Prepare two 1 mL aliquots in transfer vials. Store and send at controlled ambient temperature. Do not freeze.

Additional Information

Indicate date of birth. Due to limited stability, specimens must be received at ICL Monday – Wednesday within 4 days of collection.If advised, ICL Client Care can monitor specimen receipt to ensure timely processing.

Stability

Ambient 7 days
Refrigerated 48 hours
Frozen Unsuitable

Additional Stability Information

Freezing or prolonged storage at 4°C (>12 hours) causes loss of LD-V.

Rejection Criteria

Hemolysis Visible

Test Version

19-Jan-2024

Performance / Interpretation

Method

Electrophoresis Densitometry (LDI) & Photometric Rate (LD)

Turnaround Time

7 days

Specimen Retention Time

1 week

Results

Name Units Reference Range Conversion Factor
Lactate Dehydrogenase (LD) U/L
  • 1 - 30 d: 135 - 750
  • 31 days - 11 m: 180 - 435
  • 1 - 3 y: 160 - 370
  • 4 - 6 y: 145 - 345
  • 7 - 9 y: 143 - 290
  • 10 - 12 y: 120 - 293
  • 13 - 15 y: 110 - 283
  • 16 - 17 y: 105 - 233
  • ≥18 y: 122 - 222
LD Iso - I (Heart) %
  • 17.5 - 28.3
LD Iso - II %
  • 30.4 - 36.4
LD Iso - III %
  • 19.2 - 24.8
LD Iso - IV %
  • 9.6 - 15.6
LD Iso - V (Liver) %
  • 5.5 - 12.7

Test Location

Mayo Clinical Labs, Minnesota USA

Test Version

19-Jan-2024

Interface / Setup

Test Version

19-Jan-2024