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Immunoglobulin G (IgG) Subclasses, Serum

Test ID: IGGSUB
Test
Specimen
Performance / Interpretation
Interface / Setup

Test

Aliases/Synonyms

IgG Subclasses Panel

Method

Turbidimetry

Platform

SPA Plus™

Report Includes

IgG 1 Subclass; IgG 2 Subclass; IgG 3 Subclass; IgG 4 Subclass; Total IgG

Specimens

Serum

Test Location

Scarborough General Hospital, 3050 Lawrence Avenue, Scarborough ON M1P 2V5

Test Version

11-Mar-2025

Specimen

Specimens

Serum

Collection Containers

Gold top (clot activator & gel)

Sample Volume

1 mL

Minimum Volume

0.5 mL

Collection & Handling

Handling Information

Store and send frozen.

Additional Information

Provide date of birth and gender. The report will not include reference ranges when age and gender are not provided.

Stability

Refrigerated 3 days
Frozen 6 months

Rejection Criteria

Hemolysis Present

Test Version

11-Mar-2025

Performance / Interpretation

Method

Turbidimetry

Platform

SPA Plus™

Turnaround Time

7 days

Results

Name Units Reference Range Conversion Factor
IgG 1 Subclass g/L
  • 0 - 2 y: 1.94 - 8.42
  • 2 - 4 y: 3.15 - 9.45
  • 4 - 6 y: 3.06 - 9.45
  • 6 - 8 y: 2.88 - 9.18
  • 8 - 10 y: 4.32 - 10.20
  • 10 - 12 y: 4.23 - 10.60
  • 12 - 14 y: 3.42 - 11.50
  • 14 - 18 y: 3.15 - 8.55
  • ≥18 y: 3.82 - 9.29
 mg/L x 0.0100
IgG 2 Subclass g/L
  • 0 - 2 y: 0.23 - 3.00
  • 2 - 4 y: 0.36 - 2.25
  • 4 - 6 y: 0.61 - 3.45
  • 6 - 8 y: 0.44 - 3.75
  • 8 - 10 y: 0.72 - 4.30
  • 10 - 12 y: 0.76 - 3.55
  • 12 - 14 y: 1.00 - 4.55
  • 14 - 18 y: 0.64 - 4.95
  • ≥18 y: 2.42 - 7.00
 mg/L x 0.0100
IgG 3 Subclass g/L
  • 0 - 2 y: 0.19 - 0.85
  • 2 - 4 y: 0.17 - 0.68
  • 4 - 6 y: 0.10 - 1.22
  • 6 - 8 y: 0.16 - 0.85
  • 8 - 10 y: 0.13 - 0.85
  • 10 - 12 y: 0.17 - 1.73
  • 12 - 14 y: 0.28 - 1.25
  • 14 - 18 y: 0.23 - 1.96
  • ≥18 y: 0.22 - 1.76
 mg/L x 0.0100
IgG 4 Subclass g/L
  • 0 - 2y: 0.005 - 0.784
  • 2 - 4 y: 0.010 - 0.537
  • 4 - 6 y: 0.018 - 1.125
  • 6 - 8 y: 0.004 - 0.992
  • 8 - 10 y: 0.019 - 0.932
  • 10 - 12 y: 0.016 - 1.150
  • 12 - 14 y: 0.037 - 1.360
  • 14 - 18 y: 0.110 - 1.570
  • ≥18 y: 0.039 - 0.864
 mg/L x 0.0100
Immunoglobulin G (IgG) g/L
  • 0 - 1 y: 2.3 - 14.1
  • 1 - 4 y: 4.5 - 14.3
  • 4 - 7 y: 5.0 - 14.6
  • 7 - 10 y: 5.7 - 14.7
  • 10 - 14 y: 7.0 - 15.5
  • 14 - 20 y: 7.2 - 15.8
  • > 20 y: 6.1 - 16.2
 mg/dL x 0.0100
Measured total IgG may be approximate but not exactly equal to the calculated sum of IgG subclasses as each antibody is measured independently and is subject to slightly different variations in assay performance. Measured Total IgG is assessed for acceptable variance from the sum of the individually measured IgG Subclasses.

Test Location

Scarborough General Hospital, 3050 Lawrence Avenue, Scarborough ON M1P 2V5

Test Version

11-Mar-2025

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
IGGSUB 28900IgG1 g/L
28902IgG2 g/L
28904IgG3 g/L
28906IgG4 g/L
1621IgG g/L

Test Version

11-Mar-2025