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Hantavirus Antibodies, Serum

Test ID: HANGM

Test

Method

ELISA

Report Includes

Hantavirus IgG; Hantavirus IgM; Interpretation;

Specimens

Serum

Clinical Utility

Two major groups of hantaviruses are recognized based on clinical presentation. The first group includes Sin Nombre Virus (SNV), which causes hantavirus pulmonary syndrome, a severe and sometimes fatal form of acute respiratory distress. A second group of hantaviruses (including Seoul, Hantaan, Dobrava, and Puumala) causes hemorrhagic fever with renal syndrome, a condition not typically seen in the United States. Sera are screened for IgG and IgM antibodies recognizing the nucleocapsid protein common to all hantaviruses. The lack of IgM rules out acute SNV infection. A small number of SNV IgM postive (but Hanta IgG negative) samples represent false positive reactivity associated with acute cytomegalovirus or Epstein Barr virus infection.

Test Location

Quest Diagnostics, California USA

Test Version

30-Sep-2019

Specimen

Specimens

Serum

Sample Volume

0.5 mL

Minimum Volume

0.1 mL

Specimen Comment

Gel-separator tubes are acceptable.

Collection & Handling

Handling Information

Store and send frozen.

Stability

Ambient 7 days
Refrigerated 14 days
Frozen 30 days

Test Version

30-Sep-2019

Performance / Interpretation

Method

ELISA

Turnaround Time

7 days

Results

Name Units Reference Range Conversion Factor
Hantavirus Antibodies IgG
  • Negative
Hantavirus IgM
  • Negative
Interpretation

Test Location

Quest Diagnostics, California USA

Test Version

30-Sep-2019

Interface / Setup

Test Version

30-Sep-2019