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Lysozyme, Serum

Test ID: LYSO

Test

Aliases/Synonyms

Muramidase

Method

Enzymatic

Report Includes

Lysozyme (Muramidase)

Specimens

Serum

Clinical Utility

Lysozyme in the serum is primarily due to the degradation of granulocytes and monocytes and its concentration reflects the turnover of these cells. Increases are seen in benign and malignant processes. Serum lysozyme is elevated in patients with acute or chronic granulocytic or monocytic leukemias and levels decrease with successful treatment. Conversely, patients with lymphocytic leukemia may have depressed plasma lysozyme levels.

Test Version

19-Nov-2025

Specimen

Specimens

Serum

Collection Containers

Gold top (clot activator & gel)

Sample Volume

1.0 mL

Minimum Volume

0.5 mL

Collection & Handling

Handling Information

Centrifuge serum specimens within 1 hour of collection. Delayed separation of the serum can result in spuriously high levels of lysozyme.

Stability

Ambient 24 hours
Refrigerated 15 days
Frozen 18 days

Rejection Criteria

Hemolysis Moderate to Gross
Lipemic Gross

Test Version

19-Nov-2025

Performance / Interpretation

Method

Enzymatic

Turnaround Time

10 days

Results

Name Units Reference Range Conversion Factor
Lysozyme mcg/mL
  • 5.0 - 11.0

Test Version

19-Nov-2025

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
LYSO 62651LYSOZYME (MURAMIDASE) mcg/mL

Test Version

19-Nov-2025