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Test ID:
ENAAB
Extractable Nuclear Antigen (ENA) Antibodies, Serum
Orderable by Ontario ND
Test Overview
Clinical Utility
Specimen will be tested for antibodies to 13 nuclear antigens and the results compared to pre-established cutoffs for systemic autoimmune disease. Numeric results for the antibodies will only be reported when one antibody or more exceed the cutoff. Every report will include an interpretive Medical Decision-Support System (MDSS) comment.
Method
Multiplex Immunoassay
Result Included
ANA/ENA Screen; dsDNA Antibodies; Chromatin Antibodies; Ribosomal Protein Antibodies; SS-A 52 Antibodies; SS-A 60 Antibodies; SS-B Antibodies; Centromere-B Antibodies; Sm Antibodies; SmRNP Antibodies; RNP 68 Antibodies; RNP A Antibodies; Scl-70 Antibodies; Jo-1 Antibodies
Aliases/Synonyms
ANF; Anti-nuclear antibody; Nuclear Antibodies; ANA
Specimen
Specimen Type
Serum
Volume
Sample Volume
1 mL
Stability
| Refrigerated | Frozen |
|---|---|
| 7 days | > 7 days |
Performance & Interpretation
Turnaround Time
5 days
Results
Name
Units
Reference Range
Conversion
-
ANA/ENA ScreenNegative
-
dsDNA AntibodiesIU/mLNegative: ≤ 4 Indeterminate: 5 - 9 Positive: ≥ 10
-
Chromatin AntibodiesAI<1.0
-
Ribosomal Protein AntibodiesAI<1.0
-
SS-A 52 AntibodiesAI<1.0
-
SS-A 60 AntibodiesAI<1.0
-
SS-B AntibodiesAI<1.0
-
Centromere-B AntibodiesAI<1.0
-
Sm AntibodiesAI<1.0
-
SmRNP AntibodiesAI<1.0
-
RNP 68 AntibodiesAI<1.0
-
RNP A AntibodiesAI<1.0
-
Scl-70 AntibodiesAI<1.0
-
Jo-1 AntibodiesAI<1.0
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| ENAAB | ANA Screen | 29570 | |
| HL7 codes (Effective September 11, 2023) | Note: |
Test Version
Last Updated
2023-10-04