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Erythropoietin (EPO), Serum

Test ID: EPOQST

Test

Method

Immunoassay

Report Includes

Erythropoietin

Specimens

Serum

Clinical Utility

Elevated levels of serum erythropoietin (EPO) occur in patients with anemias due to increased red cell destruction in hemolytic anemia and also in secondary polycythemias associated with impaired oxygen delivery to the tissues, impaired pulmonary oxygen exchange, abnormal hemoglobins with increased oxygen affinity, constriction of the renal vasculature, and inappropriate EPO secretion caused by certain renal and extrarenal tumors. Normal or depressed levels may occur in anemias due to increased oxygen delivery to tissues, in hypophosphatemia, and in polycythemia vera.

Test Location

Quest Diagnostics, California USA

Test Version

30-Sep-2019

Specimen

Specimens

Serum

Sample Volume

1 mL

Minimum Volume

0.5 mL

Specimen Comment

Plasma is not suitable.

Collection & Handling

Collection Instructions

Due to diurnal variation, it is recommended that specimens be collected between 7:30 a.m. and noon. Repeat collections should be timed appropriately.

Handling Information

Store and send frozen.

Stability

Ambient 10 days
Refrigerated 18 days
Frozen 28 days

Rejection Criteria

Specimen Plasma

Test Version

30-Sep-2019

Performance / Interpretation

Method

Immunoassay

Turnaround Time

6 days

Results

Name Units Reference Range Conversion Factor
Erythropoietin mIU/mL
  • <1 y: Not established
  • 1 - 3 y: M 1.7 - 17.9; F 2.1 - 15.9
  • 4 - 6 y: M 3.5 - 21.9; F 2.9 - 8.5
  • 7 - 9 y: M 1.0 - 13.5; F 2.1 - 8.2
  • 10 - 12 y: M 1.0 - 14.0; F 1.1 - 9.1
  • 13 - 15 y: M 2.2 - 14.4; F 3.8 - 20.5
  • 16 - 18 y: M 1.5 - 15.2; F 2.0 - 14.2
  • >18 y: M 2.6 - 18.5; F 2.6 - 18.5
Reference ranges may not be valid and are not applicable if the patient is receiving recombinant erythropoietin.

Test Location

Quest Diagnostics, California USA

Test Version

30-Sep-2019

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
EPOQST 39230Erythropoietin mIU/mL

Test Version

30-Sep-2019