DUTCH Cycle Mapping Only, Dried Urine

Estradiol (x9); Estrone (x9); a-Pregnanediol (x9); b-Pregnanediol (x9); b-Pregnanediol/E2 Ratio (x9); Progesterone (x9); Creatinine

Dried Urine

For some women, testing reproductive hormones (progesterone, estrogen, etc.) on a single day is sufficient. In other scenarios, the clinical picture cannot be properly captured without mapping out the hormonal pattern throughout their menstrual cycle. The expected pattern of hormones shows relatively low estrogen levels early in the cycle, a surge around ovulation and modest levels in the latter third of the cycle (the luteal phase). Progesterone levels, on the other hand, stay relatively low until after ovulation. After ovulation levels ideally increase (>10-fold) and then drop back down at the end of the cycle. A disruption in this cycle can lead to infertility or hormonal imbalance.

Testing Method
Estrogen and progesterone metabolites for this profile are all tested (9x) by GC-MS/MS. This is the most accurate method for testing urinary reproductive hormones and their metabolites. Other options include immunoassays, LC-MS/MS or GC-MS.

Source: https://dutchtest.com/wp-content/uploads/2015/11/Cycle_Mapping_White_Paper_.pdf; Accessed 28-Oct-2016