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Erythropoietin (EPO), Serum

Test ID: EPOSTM S

Test

Method

Immunoenzymatic assay

Report Includes

Erythropoietin

Specimens

Serum

Clinical Utility

EPO is a valuable tool in diagnosing and managing conditions related to red blood cell production and kidney function. Its clinical utility includes:

  • Investigating Polycythemia by differentiating between primary and secondary causes of an increased red blood cell count or insufficient red blood cell production (Anemia).
  • Monitoring Treatment: Evaluates the effectiveness of treatments for anemia.
  • Assessing Kidney Function: Low EPO levels can indicate kidney dysfunction, while high levels might suggest other conditions.

Test Location

St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8

Test Version

13-Aug-2024

Specimen

Specimens

Serum

Collection Containers

Gold top (clot activator & gel)

Sample Volume

1.0 mL

Minimum Volume

0.5 mL

Collection & Handling

Collection Instructions

Allow samples to clot completely at room temperature prior to centrifugation. Due to diurnal variation, it is recommended that specimens be collected between 7:30 a.m. and 12 p.m. (noon).

Stability

Ambient < 8 hours
Refrigerated 24 hours
Frozen > 24 hours

Additional Stability Information

Three freeze-thaw cycles are acceptable.

Test Version

13-Aug-2024

Performance / Interpretation

Method

Immunoenzymatic assay

Turnaround Time

2 days

Results

Name Units Reference Range Conversion Factor
Erythropoietin mIU/mL
  • <1 y: Not established
  • Male 1 - 3 y: 1.7 - 17.9
  • Male 4 - 6 y: 3.5 - 21.9
  • Male 7 - 9 y: 1.0 - 13.5
  • Male 10 - 12 y: 1.0 - 14.0
  • Male 13 - 15 y: 2.2 - 14.4
  • Male 16 - 18 y: 1.5 - 15.2
  • Male >18 y: 2.6 - 18.5
  • Female 1 - 3 y: 2.1 - 15.9
  • Female 4 - 6 y: 2.9 - 8.5
  • Female 7 - 9 y: 2.1 - 8.2
  • Female 10 - 12 y: 1.1 - 9.1
  • Female 13 - 15 y: 3.8 - 20.5
  • Female 16 - 18 y: 2.0 - 14.2
  • Female >18 y: 2.6 - 18.5

Test Location

St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8

Test Version

13-Aug-2024

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
EPOSTM S 65593Erythropoietin mIU/mL

Test Version

13-Aug-2024