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Systemic Sclerosis (Scleroderma, nucleoli) Profile, Serum

Test ID: SSNAB S

Test

Method

Immunoblot

Platform

Euroimmun EUROLINE immunoblot on EUROBlotMaster and evaluated on EUROLineScan

Report Includes

Anti Scl-70 Ab (Anti Topoisomerase I antibody); Anti Centromere protein A Ab; Anti Centromere protein B Ab; Anti RP11 Ab (Anti RNA polymerase III (POLR3K) antibody); Anti RP155 Ab (Anti RNA polymerase III (POLR3A) antibody); Anti Fibrillarin (U3-RNP) Ab; Anti NOR90 Ab(Anti Nucleolus-organizing regions 90 kDa antigen antibody); Anti Th/To Ab; Anti PM-Scl 100 Ab (Anti PM/Scl Complex (100 kDa) antibody); Anti PM-Scl 75 Ab (Anti PM/Scl Complex (75 kDa) antibody); Anti Ku Ab; Anti PDGF Ab (Anti Platelet-derived growth factor receptor antibody); Anti Ro52 (TRIM21) Ab

Specimens

Serum

Test Location

St. Joseph's Hospital, 30 The Queensway, Toronto ON M6R 1B5

Test Version

12-Feb-2025

Specimen

Specimens

Serum

Collection Containers

Gold top (clot activator & gel)

Sample Volume

0.5 mL

Minimum Volume

0.3 mL

Collection & Handling

Collection Instructions

Separate as soon as possible. Store and send frozen.

Stability

Refrigerated 14 days
Frozen 60 days

Test Version

12-Feb-2025

Performance / Interpretation

Method

Immunoblot

Platform

Euroimmun EUROLINE immunoblot on EUROBlotMaster and evaluated on EUROLineScan

Turnaround Time

14 days

Results

Name Units Reference Range Conversion Factor
Anti Scl-70 Ab
  • Negative
Anti Centromere protein A Ab
  • Negative
Anti Centromere protein B Ab
  • Negative
Anti RP11 Ab
  • Negative
Anti RP155 Ab
  • Negative
Anti Fibrillarin (U3-RNP) Ab
  • Negative
Anti NOR90 Ab
  • Negative
Anti Th/To Ab
  • Negative
Anti PM-Scl 100 Ab
  • Negative
Anti PM-Scl 75 Ab
  • Negative
Anti Ku Ab
  • Negative
Anti PDGF Ab
  • Negative
Anti Ro52 (TRIM21) Ab
  • Negative

Test Location

St. Joseph's Hospital, 30 The Queensway, Toronto ON M6R 1B5

Test Version

12-Feb-2025

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
SSNAB S 63584Anti-Scl-70
63585Anti-Centromere A
63586Anti-CENP B
63614Anti-RP11
63615Anti-RP155
63616Anti-Fibrillarin (U3-RNP)
63617Anti-NOR90
63618Anti-Th/To
62081Anti-PM-Scl 100
62082Anti-PM-Scl 75
62080Anti-Ku
63622Anti-PDGF
62089Anti-Ro52 (TRIM21)
63624Interpretation

Test Version

12-Feb-2025