Anti Myelin Oligodendrocyte Glycoprotein and Anti Aquaporin4 IgG; Anti AQP4 antibody; Anti NMO antibody; Anti MOG antibody; NMOSD
Neuromyelitis Optica Spectrum Profile, Serum; test site LHSC
Test
Aliases/Synonyms
Method
Recombinant Cell-based Immunofluorescence Assay (IFA)
Report Includes
Anti-AQP4; Anti-MOG
Specimens
Important Note: Neuromyelitis Optica testing is available at multiple testing labs. Non-interfaced clients should specify the Test ID NMOSP S when ordering this test. Not doing so will cause processing delays while ICL ascertains which test you are requesting.
Clinical Utility
This test can be used to help distinguish between Multiple Sclerosis (MS) and Neuromyelitis Optica Spectrum Disorders (NMOSD).
A single autoantibody test is not diagnostic and should not be used to determine course of treatment. The test result must be evaluated with consideration of clinical presentation, patient history and other laboratory tests.
Test Location
London Health Sciences Centre, 339 Windermere Road, London ON N6A 5A5
Test Version
25-Jul-2024
Specimen
Specimens
Important Note: Neuromyelitis Optica testing is available at multiple testing labs. Non-interfaced clients should specify the Test ID NMOSP S when ordering this test. Not doing so will cause processing delays while ICL ascertains which test you are requesting.
Collection Containers
Preferred
Gold top (clot activator & gel); Red top (no additive)
Acceptable
Lavender top (EDTA); Green top (lithium or sodium heparin); Blue top (3.2% buffered citrate)
Sample Volume
2 mL
Minimum Volume
1 mL
Collection & Handling
Handling Information
Store and send frozen. Avoid freeze/thaw cycles.
Additional Information
MOG titer is performed when MOG is positive at no additional fee.
Stability
Refrigerated | 14 days |
---|---|
Frozen | 30 days |
Additional Stability Information
Avoid freeze/thaw cycles.
Test Version
25-Jul-2024
Performance / Interpretation
Method
Recombinant Cell-based Immunofluorescence Assay (IFA)
Turnaround Time
9 days
Results
Name | Units | Reference Range | Conversion Factor | |
---|---|---|---|---|
Anti-AQP4,S |
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Anti-MOG,S |
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Sample Reports
Test Location
London Health Sciences Centre, 339 Windermere Road, London ON N6A 5A5
Test Version
25-Jul-2024
Interface / Setup
HL7 Interface Codes
Order Code | Result Codes | Units |
---|---|---|
NMOSP S | 63525Anti-AQP4,S | |
63526Anti-MOG,S |
Sample Reports
Test Version
25-Jul-2024