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Lactate Dehydrogenase (LD) Isoenzyme Panel, Serum

Test ID: LDISOENZP S

Test

Method

Electrophoresis - spectrophotometry

Report Includes

Lactate Dehydrogenase (LD); Lactate Dehydrogenase Isoenzymes LD1; LD2; LD3; LD4; LD5

Specimens

Serum

Clinical Utility

Lactate dehydrogenase (LD) is present in many different organs and tissues such as liver, heart, muscles, kidney, lungs and blood. The usual designation of isoenzymes is LD-I, LD-II, LD-III, LD-IV and LD-V. LD isoenzymes tissue specificity is derived from the fact that LD subunits are synthesized in well-defined ratios and could be used in investigating unexplained causes of Total LD elevations and detection of macro-LD. Do not use LD isoenzymes to detect myocardial injury.

Test Location

Quest Diagnostics-Nichols Institute, 33608 Ortega Highway, San Juan Capistrano, CA 92675-2042

Test Version

19-Jan-2024

Specimen

Specimens

Serum

Collection Containers

Gold top (clot activator & gel)

Sample Volume

2 mL

Minimum Volume

1 mL

Collection & Handling

Handling Information

Separate within 1 hour of collection. Do not refrigerate or freeze the specimens. Store and send at ambient temperature.

Stability

Ambient 7 days
Refrigerated Unacceptable
Frozen Unacceptable

Rejection Criteria

Hemolysis Present
Specimen Received refrigerated or frozen

Test Version

19-Jan-2024

Performance / Interpretation

Method

Electrophoresis - spectrophotometry

Turnaround Time

10 days

Results

Name Units Reference Range Conversion Factor
LD U/L
  • Male
    < 1 Month: 125 -735
  • 1 - 11 Months: 170 - 450
  • 1 - 3 Years: 155 - 345
  • 4 - 6 Years: 155 - 345
  • 7 - 10 Years: 140 - 270
  • 11 - 13 Years: 110 - 250
  • 14 - 17 Years: 110 - 230
  • 18 - 49 Years: 100 - 220
  • > 49 Years: 120 - 250
  • Female
    < 1 Month: 145 - 765
  • 1 - 11 Months: 190 - 420
  • 1 - 3 Years: 165 - 395
  • 4 - 6 Years: 135 - 345
  • 7 - 10 Years: 140 - 270
  • 11 - 13 Years: 110 - 250
  • 14 - 17 Years: 110 - 230
  • 18 - 49 Years: 100 - 200
  • > 49 Years: 120 - 250
LD1 %
  • 18 - 32
LD2 %
  • 29 - 42
LD3 %
  • 14 - 30
LD4 %
  • 6 - 13
LD5 %
  • 5 - 18

Test Location

Quest Diagnostics-Nichols Institute, 33608 Ortega Highway, San Juan Capistrano, CA 92675-2042

Test Version

19-Jan-2024

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
LDISOENZP S 65324LD U/L
65325LD1 %
65326LD2 %
65327LD3 %
65328LD4 %
65329LD5 %

Test Version

19-Jan-2024