Test Overview
Method
Electrochemiluminescent immunoassay (ECLIA)
Analytical Platform
Roche CobasPRO
Result Included
Thyroid Receptor Antibodies (TRAB)
Aliases/Synonyms
TBII; Thyrotropin Binding (TBII); Thyrotropin Receptor Antibody; TSH Receptor Binding Antibody; TSI
Specimen
Specimen Type
SerumContainers
Collection Containers
Gold top (clot activator & gel);Red top (no additive)
Volume
Sample Volume
1 mL
Minimum Volume
0.5 mL
Pediatric
Minimum
0.5 mL
Comment
Collect pediatric sample in red or yellow microtainer
Patient Preparation
Elevated results are obtained with this streptavidin-biotin method for samples with extremely high biotin supplementation (concentrations > 2456 nmol/L). Avoid high biotin doses (i.e. > 300 mg/day) for three days prior to specimen collection.
Collection & Handling
Handling Information
Store and send cold or frozen.
Stability
| Ambient | Refrigerated | Frozen |
|---|---|---|
| 7 hours | 7 days | 1 year |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Specimen | Plasma |
| Hemolysis | Present |
| Lipemia | Present |
Performance & Interpretation
Turnaround Time
9 days
Results
Name
Units
Reference Range
Conversion
-
Thyroid Receptor AntibodiesIU/LNormal: < 1.8
Comment
Interpretation: Results of 1.8 or greater have a sensitivity of 97% and a specificity of 99% for Grave's disease.
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| TRAB | TRab (TSI) | 3420 |
Test Version
Last Updated
2023-08-16