TBII; Thyrotropin Binding (TBII); Thyrotropin Receptor Antibody; TSH Receptor Binding Antibody; TSI
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Thyroid Receptor Antibodies (TRAB), Serum
Test ID: TRAB
Test
Aliases/Synonyms
Method
ECLIA
Platform
Roche CobasPRO
Report Includes
Thyroid Receptor Antibodies (TRAB)
Specimens
Serum
Test Location
St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8
Test Version
16-Aug-2023
Specimen
Specimens
Serum
Collection Containers
Gold top (clot activator & gel);Red top (no additive)
Sample Volume
1 mL
Minimum Volume
0.5 mL
Patient Preparation
Elevated results are obtained with this streptavidin-biotin method for samples with extremely high biotin supplementation (concentrations > 2456 nmol/L). Avoid high biotin doses (i.e. > 300 mg/day) for three days prior to specimen collection.
Collection & Handling
Handling Information
Store and send cold or frozen.
Stability
| Ambient | 7 hours |
|---|---|
| Refrigerated | 7 days |
| Frozen | 1 year |
Rejection Criteria
| Specimen | Plasma |
|---|---|
| Hemolysis | Present |
| Lipemia | Present |
Test Version
16-Aug-2023
Performance / Interpretation
Method
ECLIA
Platform
Roche CobasPRO
Turnaround Time
9 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Thyroid Receptor Antibodies | IU/L |
|
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Interpretation: Results of 1.8 or greater have a sensitivity of 97% and a specificity of 99% for Grave's disease.
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Test Location
St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8
Test Version
16-Aug-2023
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| TRAB | 3420TRab (TSI) | IU/L |
Test Version
16-Aug-2023