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Osteocalcin, Serum/Plasma

Test ID: OSTEO
Test
Specimen
Performance / Interpretation
Interface / Setup

Test

Method

ECLIA

Platform

Roche CobasPRO

Report Includes

Osteocalcin

Specimens

Serum;Plasma

Clinical Utility

This assay detects intact Osteocalcin (amino acids 1-49) as well as the N-MID fragment (amino acids 1-43).

Test Version

12-Oct-2023

Specimen

Specimens

Serum;Plasma

Collection Containers

Preferred

Gold top (clot activator & gel);Red top (no additive)

Acceptable

Lavender top (EDTA); Green top (Na Heparin); Green top (Li Heparin)

Sample Volume

1 mL

Minimum Volume

0.5 mL

Specimen Comment

Gel-separator tubes are acceptable.

Collection & Handling

Collection Instructions

Avoid hemolysis as erythrocytes contain proteases that will degrade Osteocalcin.

Handling Information

Separate within 4 hours of collection and freeze immediately. Store and send frozen

Stability

Ambient 8 hours
Refrigerated 3 days
Frozen 3 months

Rejection Criteria

Hemolysis Present

Test Version

12-Oct-2023

Performance / Interpretation

Method

ECLIA

Platform

Roche CobasPRO

Turnaround Time

9 days

Results

Name Units Reference Range Conversion Factor
Osteocalcin, N-MID µg/L
  • Male:
  • 5m - 7 y: 39 - 121
  • 8 y - 10 y: 66 - 182
  • 11 y - 13 y: 85 - 232
  • 14 y - 16 y: 70 - 336
  • 17 y - 18 y: 43 - 237
  • 19 y - 29 y: 24 - 70
  • 30 y - 50 y: 14 - 42
  • ≥51 y: 13 - 48
  • Female:
  • 5m - 7 y: 44 - 130
  • 8 y - 10 y: 73 - 206
  • 11 y - 13 y: 77 - 262
  • 14 y - 16 y: 33 - 222
  • 17 y - 18 y: 24 - 99
  • ≥19 y: 11 - 46

Test Version

12-Oct-2023

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
OSTEO 36478N-MID Osteocalcin ug/L

Test Version

12-Oct-2023