Amitriptyline; Nortriptyline; Amitriptyline + Nortriptyline, Total
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            Amitriptyline and Nortriptyline, Serum/Plasma
Test ID: AMIT
                    
                    
                Test
Method
LC-MS/MS
Report Includes
Specimens
            Avoid gel separator tubes; Serum; Plasma (EDTA)        
    Test Version
14-Oct-2022
Specimen
Specimens
            Avoid gel separator tubes; Serum; Plasma (EDTA)        
    Sample Volume
3 mL
Specimen Comment
Avoid gel separator tubes.
Collection & Handling
Collection Instructions
Collect trough specimen (i.e. collected within 1 hours prior to next dose or at least 12 hours post-dose.)
Handling Information
Separate within 2 hours.
Stability
| Ambient | 5 days | 
|---|---|
| Refrigerated | 2 weeks | 
| Frozen | 6 months | 
Rejection Criteria
| Specimen | Gel-separator tube | 
|---|
Test Version
14-Oct-2022
Performance / Interpretation
Method
LC-MS/MS
Turnaround Time
5 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Amitriptyline | ng/mL | 
                                                                                    
  | 
                                    ||
| Nortriptyline | ng/mL | 
                                                                                    
  | 
                                    ||
| Amitriptyline + Nortriptyline, Total | ng/mL | 
                                                                                    
  | 
                                    ||
| 
                                             (Effective 18-Oct-2022) 
                                         | 
                                    ||||
Test Version
14-Oct-2022
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units | 
|---|---|---|
| AMIT | 7566Amitriptyline | ng/mL | 
| 7567Nortriptyline | ng/mL | |
| 7568Combined Metabolite | ng/mL | 
Test Version
14-Oct-2022