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Hepatitis E Virus (HEV) Antibodies IgG and IgM, Serum

Test ID: HEVAB S

Test

Method

ELISA

Report Includes

HEV IgG; HEV IgM

Specimens

Serum

Clinical Utility

Hepatitis E virus (HEV) is the major etiologic agent of enterically transmitted non-A, non-B hepatitis worldwide and has a high case-fatality rate in pregnant women. Both IgM and IgG antibody to HEV (anti-HEV) are produced following infection. The titer of IgM anti-HEV declines rapidly during early convalescence; IgG anti-HEV persists and appears to provide at least short-term protection against disease.

Test Location

Quest Diagnostics, California USA

Test Version

1-Mar-2023

Specimen

Specimens

Serum

Collection Containers

Gold top (clot activator & gel)

Sample Volume

1 mL

Minimum Volume

0.2 mL

Collection & Handling

Handling Information

Store and send cold or frozen.

Stability

Ambient 7 days
Refrigerated 14 days
Frozen 30 days

Test Version

1-Mar-2023

Performance / Interpretation

Method

ELISA

Turnaround Time

10 days

Results

Name Units Reference Range Conversion Factor
HEV IgG
  • Not detected
HEV IgM
  • Not Detected

Hepatitis E virus (HEV) is a major cause of enteric non-A hepatitis worldwide. Both HEV IgM and IgG are typically detected within one month after infection; IgM persists for about two months, whereas IgG levels persist for months to years after recovery. Approximately 20% of the US population is positive for HEV IgG, indicating that HEV exposure is more common than previously thought.

Test Location

Quest Diagnostics, California USA

Test Version

1-Mar-2023

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
HEVAB 63055HEV IGG
63056HEV IGM

Test Version

1-Mar-2023