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Chlordiazepoxide LC-MS/MS, Serum
Test ID: CLDIAZSM S
Test
Aliases/Synonyms
Method
LC-MS/MS
Report Includes
Chlordiazepoxide; Nordiazepam
Specimens
Gel-separator tubes are not acceptable; Serum
Test Location
St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8
Test Version
13-Jan-2023
Specimen
Specimens
Gel-separator tubes are not acceptable; Serum
Collection Containers
Red top (no additive)
Sample Volume
1 mL
Specimen Comment
Avoid gel-separator tubes.
Collection & Handling
Handling Information
Store and submit specimen protected from light in an amber vial.
Separate and aliquot within 2 hours. Store and send cold or frozen.
Stability
| Ambient | 24 hours |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |
Rejection Criteria
| Specimen | Gel tube or not protected from light |
|---|
Test Version
13-Jan-2023
Performance / Interpretation
Method
LC-MS/MS
Turnaround Time
12 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Chlordiazepoxide | ng/mL |
|
nmol/L x 0.287 | |
| Nordiazepam | ng/mL |
|
nmol/L x 0.266 | |
|
Therapeutic ranges based on Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: update 2017 and Tietz Textbook of Clinical Chemistry and Molecular Diagnostics 6th ed pp. 1808.
|
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Test Location
St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8
Test Version
13-Jan-2023
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| CHDIAZSM S | 64774Chlordiazepam | ng/mL |
| 64775Nordiazepam | ng/mL |
Test Version
13-Jan-2023