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Shrimp rPen a 1 Tropomyosin (f351) IgE, Serum

Test ID: RPENA1
Test
Specimen
Performance / Interpretation
Interface / Setup

Test

Method

ImmunoCAP™

Method Description

ImmunoCAP™ assays are based on binding of allergen-specific IgE antibodies in serum to allergen (extract or allergen molecule) coupled in excess to a solid phase. Bound IgE is subsequently detected with enzyme-labeled anti-human IgE, where the fluorescence intensity is proportional to the amount of allergen-specific IgE.

Platform

Phadia

Report Includes

Shrimp rPen a 1 Tropomyosin (f351) IgE

Specimens

Serum

Clinical Utility

This ImmunoCAP Allergen Component test measures IgE antibodies specific to individual molecular allergens. These allergens, which are purified or recombinant proteins, offer the unique opportunity to assess a persons allergic sensitization pattern.

Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of symptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.

Test Location

Hamilton General Hospital, 237 Barton St E, Hamilton ON L8L 2X2

Test Version

17-Nov-2023

Specimen

Specimens

Serum

Collection Containers

Gold top (clot activator & gel)

Sample Volume

1 mL

Minimum Volume

50 uL

Specimen Comment

Submit enough specimen for number of IgE tests ordered. Each test requires 50 µL and 2 mL is sufficient for 10-12 tests.

Collection & Handling

Handling Information

Store and send frozen

Additional Information

Refer to the list of available IgE Allergen Tests.

Stability

Refrigerated 3 days
Frozen 6 months

Test Version

17-Nov-2023

Performance / Interpretation

Method

ImmunoCAP™

Method Description

ImmunoCAP™ assays are based on binding of allergen-specific IgE antibodies in serum to allergen (extract or allergen molecule) coupled in excess to a solid phase. Bound IgE is subsequently detected with enzyme-labeled anti-human IgE, where the fluorescence intensity is proportional to the amount of allergen-specific IgE.

Platform

Phadia

Turnaround Time

10 days

Results

Name Units Reference Range Conversion Factor
Shrimp rPen a 1 Tropomyosin (f351) IgE kU/L
  • <0.35

Recombinant non-glycosylated form of 36-kDa muscle protein tropomyosin found in shrimp.
Tropomyosin identified as major Shrimp allergen. Heat stable and found in both raw and cooked shrimp.
Tropomyosin detected in sera of more than 80% of all subjects allergic to shrimp.
Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of asymptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.
Use caution when interpreting drug, venom and potential anaphylactic allergen results.

Test Location

Hamilton General Hospital, 237 Barton St E, Hamilton ON L8L 2X2

Test Version

17-Nov-2023

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
RPENA1 6966ALLERGEN FOOD: RPEN A 1 TROPOMYOSIN, SHRIMP IGE (KU/L) F351 kU/L

Test Version

17-Nov-2023