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Histone Antibodies, Serum

Test ID: HISABQST S

Test

Method

Enzyme Immunoassay (EIA)

Specimens

Serum

Clinical Utility

Histone antibody is present in 80-95% of patients with drug-induced Systemic Lupus Erythematosus (SLE), 20-50% of patients with idiopathic SLE, and infrequently in patients with other autoimmune connective tissue diseases.

Test Location

Quest Diagnostics, California USA

Test Version

29-Sep-2022

Specimen

Specimens

Serum

Collection Containers

SST (Gold Top)

Sample Volume

1 mL

Minimum Volume

0.3 mL

Patient Preparation

Overnight fasting preferred

Collection & Handling

Handling Information

Store and send cold or frozen.

Stability

Ambient 24 hours
Refrigerated 14 days
Frozen 30 days

Test Version

29-Sep-2022

Performance / Interpretation

Method

Enzyme Immunoassay (EIA)

Turnaround Time

10 days

Results

Name Units Reference Range Conversion Factor
Histone Antibodies U
  • < 1.0 Negative
  • 1.0 - 1.5 Weak Positive
  • 1.6 - 2.5 Moderate Positive
  • > 2.5 Strong Positive

Test Location

Quest Diagnostics, California USA

Test Version

29-Sep-2022

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
HISABQST S 64650HISTONE ANTIBODIES U

Test Version

29-Sep-2022