Renin Activity
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Renin Activity LC-MS/MS, Plasma
Test ID: RENSTM P
Test
Method
LC-MS/MS
Report Includes
Specimens
Plasma (EDTA)
Test Location
St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8
Test Version
30-Aug-2022
Specimen
Specimens
Plasma (EDTA)
Collection Containers
Lavender top (EDTA)
Sample Volume
1 mL
Patient Preparation
Patient should liberalize (not restrict) sodium intake. The following medications should be held for 4 weeks prior to testing or for as long as is clinically feasible: spironolactone, eplerenone, amiloride, triamterene, potassium-wasting diuretics, confectionary licorice, or chewing tobacco. Please refer to the 2016 Endocrine Society Practice Guidelines for more information (Funder et al., J Clin Endocrinol Metab 2016).
Collection & Handling
Collection Instructions
Collect blood midmorning, after the patient has been up (sitting, standing, or walking) for at least 2 hours and then seated for 5-15 minutes.
Handling Information
Separate and freeze immediately. Indicate date and time of collection and whether the patient was supine or upright.
Stability
| Ambient | 6 hours |
|---|---|
| Refrigerated | 4 hours |
| Frozen | 30 days |
Additional Stability Information
Prolonged refrigerated storage may lead to a false increase due to cryoactivation of prorenin to renin. If the specimen thaws, it is unsuitable for analysis.
Rejection Criteria
| Specimen | Not frozen |
|---|
Test Version
30-Aug-2022
Performance / Interpretation
Method
LC-MS/MS
Turnaround Time
8 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Renin Activity | ng/mL/hr |
|
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Test Location
St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8
Test Version
30-Aug-2022
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| RENSTM P | 64445Renin Activity, plasma | ng/mL/hr |
Test Version
30-Aug-2022