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Carbohydrate-deficient Transferrin (CDT) (Alcohol Use), Serum

Test ID: TRANSCD

Test

Method

Nephelometry

Report Includes

Transferrin; Carbohydrate Deficient Transferrin (CDT); %CDT

Specimens

Serum

Clinical Utility

Heavy alcohol use (defined as >4 or 5 beverages per day for two weeks or more) is commonly associated with elevated CDT levels as are certain liver diseases such as primary biliary cirrhosis and chronic active hepatitis and in some patients with genetic D variants of transferrin. CDT isoform analysis for evaluation of Congenital Disorders of Glycosylation (CDG) is also available: Carbohydrate Deficient Transferrin (CDT) for Congenital Disorders of Glycosylation (CDG), Serum.

Test Location

Quest Diagnostics, Virginia USA

Test Version

18-Mar-2020

Specimen

Specimens

Serum

Collection Containers

Gold top (SST)

Sample Volume

1.0 mL

Minimum Volume

0.5 mL

Collection & Handling

Handling Information

Serum samples must be fully coagulated, centrifuged within 1 hour of collection, and must not contain any particles or traces of fibrin after centrifugation. Transfer serum to a clean, plastic, screw-cap vial.

Stability

Ambient 24 hours
Refrigerated 7 days
Frozen 90 days

Rejection Criteria

Hemolysis Gross
Lipemia Gross
Other Grossly icteric

Test Version

18-Mar-2020

Performance / Interpretation

Method

Nephelometry

Turnaround Time

7 days

Results

Name Units Reference Range Conversion Factor
Carbohydrate Deficient Transferrin (CDT) mg/L
  • 28.1 - 76.0
Transferrin mg/dL
  • 188 - 341
%CDT %
  • <2.5

Test Location

Quest Diagnostics, Virginia USA

Test Version

18-Mar-2020

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
TRANSCD 62044TRANSFERRIN mg/dL
62045%CDT %
62046CDT mg/L

Test Version

18-Mar-2020