Carbohydrate-deficient Transferrin (CDT) (Alcohol Use), Serum
Test Overview
Clinical Utility
Heavy alcohol use (defined as >4 or 5 beverages per day for two weeks or more) is commonly associated with elevated CDT levels as are certain liver diseases such as primary biliary cirrhosis and chronic active hepatitis and in some patients with genetic D variants of transferrin. CDT isoform analysis for evaluation of Congenital Disorders of Glycosylation (CDG) is also available: Carbohydrate Deficient Transferrin (CDT) for Congenital Disorders of Glycosylation (CDG), Serum.
Method
Nephelometry
Result Included
Transferrin; Carbohydrate Deficient Transferrin (CDT); %CDT
Specimen
Specimen Type
SerumContainers
Collection Containers
Gold top (SST)
Volume
Sample Volume
1.0 mL
Minimum Volume
0.5 mL
Collection & Handling
Handling Information
Serum samples must be fully coagulated, centrifuged within 1 hour of collection, and must not contain any particles or traces of fibrin after centrifugation. Transfer serum to a clean, plastic, screw-cap vial.
Stability
| Ambient | Refrigerated | Frozen |
|---|---|---|
| 24 hours | 7 days | 90 days |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Hemolysis | Gross |
| Lipemia | Gross |
| Other | Grossly icteric |
Performance & Interpretation
Turnaround Time
7 days
Results
-
Carbohydrate Deficient Transferrin (CDT)mg/L28.1 - 76.0
-
Transferrinmg/dL188 - 341
-
%CDT%<2.5
Referral Location
Out-of-Country
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| TRANSCD | TRANSFERRIN | 62044 | mg/dL |
| %CDT | 62045 | % | |
| CDT | 62046 | mg/L |
Test Version
Last Updated
2020-03-18