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Lipoprotein Profile by Nuclear Magnetic Resonance (NMR), Serum

Test ID: NMRLP S
Orderable by Ontario ND
Test
Specimen
Performance / Interpretation
Interface / Setup

Test

Aliases/Synonyms

Lipoprotein particles; LDL particle number; HDL particle number

Method

Nuclear Magnetic Resonance (NMR)

Method Description

Lipoprotein particles are quantified in serum by nuclear magnetic resonance (NMR). The deconvoluting algorithm used is the AXINON Mayo LP Profiler software.(AXINON System User Manual Version 1.3.2, 3/2018)

Report Includes

LDL Particles; HDL Particles; LDL Cholesterol (NMR), S

Specimens

Serum

Clinical Utility

Assessment and management of a patient’s risk for atherosclerotic cardiovascular disease.
Identifying residual risk that may be present in some patients on cholesterol targeting treatment.

Test Location

Mayo Clinical Labs, Minnesota USA

Test Version

1-Dec-2020

Specimen

Specimens

Serum

Collection Containers

Red top (no additive)

Sample Volume

1.5 mL

Minimum Volume

1.0 mL

Patient Preparation

Fasting overnight (12 – 14 hours) is required. On night before examination, evening meal should be eaten before 6 p.m. and should contain no fatty foods.
Patient must not consume any alcohol for 24 hours before the specimen is collected.

Collection & Handling

Collection Instructions

Allow isopropyl alcohol (from phlebotomy site prep) to dry thoroughly before venipuncture.

Handling Information

Store and send frozen.

Stability

Ambient 8 hours
Refrigerated 7 days
Frozen 14 days

Rejection Criteria

Hemolysis Gross
Lipemia Gross
Other Grossly icteric

Test Version

1-Dec-2020

Performance / Interpretation

Method

Nuclear Magnetic Resonance (NMR)

Method Description

Lipoprotein particles are quantified in serum by nuclear magnetic resonance (NMR). The deconvoluting algorithm used is the AXINON Mayo LP Profiler software.(AXINON System User Manual Version 1.3.2, 3/2018)

Turnaround Time

7 days

Results

Name Units Reference Range Conversion Factor
LDL Particles nmol/L
  • Desirable: <1000
  • Above Desirable: 1000 - 1299
  • Borderline high: 1300 - 1599
  • High: 1600 - 2000
  • Very high: ≥2000
HDL Particles mcmol/L
  • >30
LDL Cholesterol (NMR) mg/dL
  • Desirable: <100
  • Above Desirable: 100 - 129
  • Borderline high: 130 - 159 mg/dL
  • High: 160 - 189 mg/dL
  • Very high: ≥190
NMR LDL-C results compare to measured LDL-C but may be discrepant from estimated LDL-C values.

Test Location

Mayo Clinical Labs, Minnesota USA

Test Version

1-Dec-2020

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
NMRLP S 63205LDL Particles, S nmol/L
63206HDL Particles, S mcmol/L
63207LDL Cholesterol (NMR), S mg/dL

Test Version

1-Dec-2020