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Amiodarone and Metabolite, Serum

Test ID: AMIO

Test

Method

LC-MS/MS

Report Includes

Amiodarone; Desethylamiodarone

Specimens

Avoid gel separator tubes; Serum

Test Location

University Health Network, 200 Elizabeth St, 11E-444, Toronto ON M5G 2C4

Test Version

18-Oct-2024

Specimen

Specimens

Avoid gel separator tubes; Serum

Sample Volume

3 mL

Minimum Volume

1.0 mL

Specimen Comment

Avoid gel separator tubes.

Collection & Handling

Collection Instructions

To monitor therapy, draw trough specimen prior to next dose.

Handling Information

Store and send frozen.

Stability

Refrigerated 72 hours
Frozen 2 Years (-70°C)

Rejection Criteria

Specimen Gel-separator tube

Test Version

18-Oct-2024

Performance / Interpretation

Method

LC-MS/MS

Turnaround Time

7 days

Results

Name Units Reference Range Conversion Factor
Amiodarone mg/L
  • 1.0 - 2.0
  • Toxic: > 2.0
Effective October 17, 2024, a calibration adjustment will result in an average decrease of 0.25mg/L in serum amiodarone and metabolite values.
Desethylamiodarone mg/L
  • No Therapeutic range established.
Effective October 17, 2024, a calibration adjustment will result in an average decrease of 0.25mg/L in serum amiodarone and metabolite values.

Test Location

University Health Network, 200 Elizabeth St, 11E-444, Toronto ON M5G 2C4

Test Version

18-Oct-2024

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
AMIO 2541Amiodarone mg/L
28342Desethylamiodarone Desethylamiodarone
40002Test Comment

Test Version

18-Oct-2024