CRMP-5-IgG Western Blot
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Collapsin Response-Mediator Protein-5-IgG (CRMP-5-IgG) Western Blot, Serum
Test ID: CRMP S
Test
Method
Western Blot
Method Description
Western blot is performed on denatured full-length recombinant human collapsin response-mediator protein-5 (CRMP-5), reduced and subjected to electrophoresis on 10% polyacrylamide gel. IgG is detected autoradiographically by enhanced chemiluminescence.(Yu Z, Kryzer TJ, Griesmann GE, et al: CRMP-5 neuronal autoantibody: marker of lung cancer and thymoma-related autoimmunity. Ann Neurol 2001 February;49[2]:146-154)
Report Includes
Specimens
Serum
Clinical Utility
This testing is recommended in cases of chorea, vision loss, cranial neuropathy and myelopathy.
Clinical Information at external website.
Test Location
Mayo Clinical Labs, Minnesota USA
Test Version
9-Dec-2019
Specimen
Specimens
Serum
Sample Volume
1.5 mL
Minimum Volume
1 mL
Specimen Comment
Gel-separator tubes are acceptable.
Collection & Handling
Handling Information
Store and send frozen
Stability
| Ambient | 72 hours |
|---|---|
| Refrigerated | 28 days |
| Frozen | 28 days |
Rejection Criteria
| Hemolysis | Gross |
|---|---|
| Lipemia | Gross |
| Other | Grossly icteric |
Test Version
9-Dec-2019
Performance / Interpretation
Method
Western Blot
Method Description
Western blot is performed on denatured full-length recombinant human collapsin response-mediator protein-5 (CRMP-5), reduced and subjected to electrophoresis on 10% polyacrylamide gel. IgG is detected autoradiographically by enhanced chemiluminescence.(Yu Z, Kryzer TJ, Griesmann GE, et al: CRMP-5 neuronal autoantibody: marker of lung cancer and thymoma-related autoimmunity. Ann Neurol 2001 February;49[2]:146-154)
Turnaround Time
10 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| CRMP-5-IgG Western Blot | None |
|
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Test Location
Mayo Clinical Labs, Minnesota USA
Test Version
9-Dec-2019
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| CRMP S | 63135CRMP-5-IgG Western Blot, S | None |
Test Version
9-Dec-2019