Vitamin K
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Vitamin K, Plasma/Serum
Test ID: VITK P
Test
Method
Chromatography/Mass Spectrometry
Report Includes
Specimens
Gel-separator tubes are not acceptable; Serum; Plasma
Clinical Utility
Vitamin K is a required co-factor for the synthesis of factors 2, 7, 9, and 10 and proteins C and S. Deficiencies of vitamin K lead to bleeding. Coumadin (warfarin) acts as an anticoagulant because it is a vitamin K antagonist.
Test Location
Quest Diagnostics, California USA
Test Version
15-Dec-2022
Specimen
Specimens
Gel-separator tubes are not acceptable; Serum; Plasma
Collection Containers
Preferred
Lavender top (EDTA)
Acceptable
Red top (no additive)
Sample Volume
1 mL
Minimum Volume
0.5 mL
Specimen Comment
Avoid gel-separator tubes.
Patient Preparation
Fasting for a minimum of 8 hours required. Patient should refrain from eating liver and taking multivitamins or Vitamin K at least 24 hours before sample collection.
Collection & Handling
Handling Information
Separate within 1 hour of collection and transfer to amber vial to protect from light. Freeze immediately.
If unable to centrifuge immediately, sample should be covered with aluminum foil immediately and placed on ice until plasma can be separated from cells. Store and send frozen. Samples received frozen but not protected from light are acceptable.
Stability
| Ambient | 24 hours |
|---|---|
| Refrigerated | 24 hours |
| Frozen | 90 days |
Additional Stability Information
If the specimen thaws, it is unsuitable for analysis.
Rejection Criteria
| Hemolysis | Gross |
|---|---|
| Lipemia | Gross |
| Specimen | Not frozen or Gel tube |
Test Version
15-Dec-2022
Performance / Interpretation
Method
Chromatography/Mass Spectrometry
Turnaround Time
10 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Vitamin K | pg/mL |
|
||
Test Location
Quest Diagnostics, California USA
Test Version
15-Dec-2022
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| VITK P | 63045Vitamin K | pg/mL |
Test Version
15-Dec-2022