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Thyroid Stimulating Immunoglobulin (TSI) Bioassay, Serum

Test ID: TSIQST

Test

Method

in vitro bioassay

Report Includes

Thyroid Stimulating Immunoglobulin (TSI)

Specimens

Serum

Clinical Utility

Graves’ disease is a classic form of hyperthyroid disease. It is caused by IgG immunoglobulins, collectively known as thyroid stimulating immunoglobulins (TSI). Patients who are candidates for antithyroid drug therapy may not respond to this treatment when TSI levels are markedly elevated. The determination of TSI can also assist in predicting hyperthyroidism in neonates, due to placental transmission of the immunoglobulins from a mother with hyperthyroidism.

Test Location

Quest Diagnostics, California USA

Test Version

9-May-2023

Specimen

Specimens

Serum

Collection Containers

Gold top (clot activator & gel)

Sample Volume

1.0 mL

Minimum Volume

0.2 mL

Collection & Handling

Handling Information

Store and send cold or frozen.

Stability

Ambient Unacceptable
Refrigerated 21 days
Frozen 60 days

Rejection Criteria

Specimen Plasma
Hemolysis Gross
Lipemia Gross
Icteric Gross

Test Version

9-May-2023

Performance / Interpretation

Method

in vitro bioassay

Turnaround Time

9 days

Results

Name Units Reference Range Conversion Factor
TSI % Baseline
  • <140

Test Location

Quest Diagnostics, California USA

Test Version

9-May-2023

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
TSIQST 38472TSI % baseline

Test Version

9-May-2023