Thyroid Stimulating Immunoglobulin (TSI)
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Thyroid Stimulating Immunoglobulin (TSI) Bioassay, Serum
Test ID: TSIQST
Test
Method
in vitro bioassay
Report Includes
Specimens
Serum
Clinical Utility
Graves’ disease is a classic form of hyperthyroid disease. It is caused by IgG immunoglobulins, collectively known as thyroid stimulating immunoglobulins (TSI). Patients who are candidates for antithyroid drug therapy may not respond to this treatment when TSI levels are markedly elevated. The determination of TSI can also assist in predicting hyperthyroidism in neonates, due to placental transmission of the immunoglobulins from a mother with hyperthyroidism.
Test Location
Quest Diagnostics, California USA
Test Version
9-May-2023
Specimen
Specimens
Serum
Collection Containers
Gold top (clot activator & gel)
Sample Volume
1.0 mL
Minimum Volume
0.2 mL
Collection & Handling
Handling Information
Store and send cold or frozen.
Stability
| Ambient | Unacceptable |
|---|---|
| Refrigerated | 21 days |
| Frozen | 60 days |
Rejection Criteria
| Specimen | Plasma |
|---|---|
| Hemolysis | Gross |
| Lipemia | Gross |
| Icteric | Gross |
Test Version
9-May-2023
Performance / Interpretation
Method
in vitro bioassay
Turnaround Time
9 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| TSI | % Baseline |
|
||
Test Location
Quest Diagnostics, California USA
Test Version
9-May-2023
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| TSIQST | 38472TSI | % baseline |
Test Version
9-May-2023