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Thioridazine and Metabolite, Serum/Plasma

Test ID: THIORQST

Test

Aliases/Synonyms

Mellaril®

Method

Gas Chromatography

Report Includes

Thioridazine; Mesoridazine

Specimens

Avoid gel separator tubes; Serum; Plasma (EDTA)

Clinical Utility

Thioridazine is a phenothiazine for treating psychosis. Monitoring its level is important to optimize therapy, to avoid toxicity, and to assure compliance.

https://testdirectory.questdiagnostics.com/test/test-detail/23232/thioridazine-and-metabolite?q=23232&cc=MET, Accessed 12-Jun-2019.

Test Location

Quest Diagnostics, California USA

Test Version

30-Sep-2019

Specimen

Specimens

Avoid gel separator tubes; Serum; Plasma (EDTA)

Sample Volume

2 mL

Minimum Volume

0.7 mL

Specimen Comment

Avoid gel separator tubes.

Stability

Ambient 8 days
Refrigerated 8 days
Frozen 1 Year

Rejection Criteria

Specimen Gel-separator tube

Test Version

30-Sep-2019

Performance / Interpretation

Method

Gas Chromatography

Turnaround Time

10 days

Results

Name Units Reference Range Conversion Factor
Thioridazine ng/mL
  • See note below

Steady-state serum concentration during chronic oral administration of 400 mg daily: 140 - 2600 ng/mL.

Therapeutic steady-state concentrations may overlap levels associated with toxicity.

Mesoridazine ng/mL
  • Therapeutic range: 100 - 1400

Test Location

Quest Diagnostics, California USA

Test Version

30-Sep-2019

Interface / Setup

Test Version

30-Sep-2019