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Porphyrins Quantitation and Fractionation, Serum/Plasma

Test ID: PORPHQ P

Test

Method

HPLC

Report Includes

Uroporphyrin; Heptacarboxyporphyrin; Hexacarboxyporphyrin; Pentacarboxyporphyrin; Coproporphyrin; Protoporphyrin; Total Porphyrins; Interpretation

Specimens

Gel-separator tubes are not acceptable; Serum; Plasma (EDTA); Plasma (Na Heparin)

Test Location

Quest Diagnostics, California USA

Test Version

16-Jun-2021

Specimen

Specimens

Gel-separator tubes are not acceptable; Serum; Plasma (EDTA); Plasma (Na Heparin)

Collection Containers

Preferred

Plasma (Na Heparin) green top

Acceptable

Serum red top; Plasma (EDTA) lavender top

Sample Volume

2 mL

Minimum Volume

0.4 mL

Specimen Comment

Avoid gel separator tubes.

Collection & Handling

Collection Instructions

Collect in foil-covered tube to protect from light. Avoid hemolysis.

Handling Information

Store and submit specimen protected from light in an amber vial.
Freeze immediately after separation. Store and send frozen.

Stability

Ambient 8 hours
Refrigerated 8 hours
Frozen 90 days

Rejection Criteria

Hemolysis Present
Specimen Gel separator tube, not frozen or not protected from light

Test Version

16-Jun-2021

Performance / Interpretation

Method

HPLC

Turnaround Time

11 days

Results

Name Units Reference Range Conversion Factor
Uroporphyrin µg/L
  • ≤0.2
Heptacarboxyporphyrin µg/L
  • ≤0.2
Hexacarboxyporphyrin µg/L
  • ≤0.3
Pentacarboxyporphyrin µg/L
  • ≤0.4
Coproporphyrin µg/L
  • ≤0.8
Protoporphyrin µg/L
  • 0.4 - 4.8
Total Porphyrins µg/L
  • 1.0 - 5.6
Interpretation

Test Location

Quest Diagnostics, California USA

Test Version

16-Jun-2021

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
PORPHQ P 39600UROPORPHYRIN mcg/L
39602HEPTACARBOXYPORPHYRIN mcg/L
39604HEXACARBOXYPORPHYRIN mcg/L
39606PENTACARBOXYPORPHYRIN mcg/L
39608COPROPORPHYRIN mcg/L
39610PROTOPORPHYRIN mcg/L
39612TOTAL PORPHYRINS mcg/L
39614INTERPRETATION

Test Version

16-Jun-2021