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Test ID:
NFLC SP
Neurofilament Light Chain (NfL), Serum/Plasma (Test Site St. Michael’s Hospital)
Test Overview
Method
Electrochemiluminescent immunoassay (ECLIA)
Analytical Platform
Roche
Result Included
Neurofilament Light Chain
Specimen
Specimen Type
SerumPlasma (Li heparin)
Important Note: TEST ID NFLC SP
Non-interfaced clients should specify the Test ID TEST ID NFLC SP when ordering this test. Not doing so will cause processing delays while ICL ascertains which test you are requesting.
Similar testing is available for clinical use at The Ottawa Hospital: Neurofilament Light Chain (NfL), Serum/Plasma
Containers
Preferred Containers
Gold top (clot activator & gel)
Acceptable Containers
Green top (lithium heparin)
Volume
Sample Volume
1.0 mL
Minimum Volume
0.4 mL
Patient Preparation
High dose biotin supplementation may interfere with analysis – patients should stop biotin consumption at least 72 hours prior to the collection of a sample.
Collection & Handling
Handling Information
Store and send frozen.
Stability
| Ambient | Refrigerated | Frozen |
|---|---|---|
| 1 day | 14 days | 3 years |
Stable up to 3 freeze-thaw cycles.
Performance & Interpretation
Turnaround Time
8 days
Results
Name
Units
Reference Range
Conversion
-
Comment
Serum NfL levels in healthy individuals are about 2.5% of the levels in CSF and correlate highly with the concentrations in CSF.
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| NFLC SP | Neurofilament Light Chain | 65355 | pg/mL |
Test Version
Last Updated
2025-07-30