Test Overview
Method
Enzyme-linked immunosorbent assay (ELISA)
Analytical Platform
Euroimmun Analyzer I
Method Description
This assay DOES NOT quantitate C1q protein. For C1q protein quantitation refer to Complement Component C1q, Serum/Plasma
Result Included
Immune Complexes
Aliases/Synonyms
Circulating Immune Complexes; CIC; C1q binding Immune complex
Specimen
Specimen Type
SerumPlasma (EDTA)
Volume
Sample Volume
1.0 mL (0.5 mL x 2)
Minimum Volume
0.2 mL
Patient Preparation
Fasting sample preferred.
Collection & Handling
Handling Information
Separate within 1 hour of collection. Store and send frozen. Avoid multiple freeze/thaw.
Additional Information
Submission of duplicate aliquots is recommended in case repeat analysis is required. Samples should not be heat inactivated. Heat inactivation results in false positive results. Rheumatoid Factor may interfere with analysis. Indicate if the patient is positive for RF.
Stability
| Refrigerated | Frozen |
|---|---|
| 7 days | > 7 days |
Performance & Interpretation
Turnaround Time
20 days
Results
-
Immune ComplexesRU/mLNegative: ≤19
Comment
Immune Complexes (CIC) as measured by C1q binding are found sporadically in the normal population as a result of infection and can also be elevated after eating. Results from different technologies, methodologies and manufacturer's kits may vary widely due to differences in standardization.
CIC testing is used to aid diagnosis only. CIC results are not diagnostic proof of the presence of absence of disease. Review the results in conjunction with history, and other diagnostic and serological tests.
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| C1QBIND | Immune Complex | 28713 | RU/mL |
Test Version
Last Updated
2023-03-23