Lepidoglyphus destructor (d71) IgE, Serum

Test Overview

Clinical Utility

In patients suffering from extrinsic asthma, hay fever or atopic eczema, symptoms develop after exposure to specific allergens. This immediate (atopic or anaphylactic) type of allergy is a function of a special type of serum antibodies belonging to the IgE class of immunoglobulins.

Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of symptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.

Analytical Platform

Phadia

Method Description

ImmunoCAP™ assays are based on binding of allergen-specific IgE antibodies in serum to allergen (extract or allergen molecule) coupled in excess to a solid phase. Bound IgE is subsequently detected with enzyme-labeled anti-human IgE, where the fluorescence intensity is proportional to the amount of allergen-specific IgE.

Result Included

Lepidoglyphus destructor (d71) IgE

Specimen

Specimen Type

Serum

Volume

Sample Volume

1 mL

Specimen Comment

Submit enough specimen for number of IgE tests ordered. Each test requires 50 µL and 2 mL is sufficient for 10-12 tests.

Collection & Handling

Handling Information

Store and send frozen.

Additional Information

Refer to the list of available IgE Allergen Tests.

Stability

Refrigerated	Frozen
3 days	6 Months

Performance & Interpretation

Turnaround Time

10 days

Results

Lepidoglyphus Dest. (d71), IgE

KU/L

<0.35

Comment

Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of symptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.
Use caution when interpreting drug, venom and potential anaphylactic allergen results.

Specific IgE		Class	Interpretive Comments
< 0.35	kU/L	0	Absent or undetectable allergen specific IgE
0.35 - 0.69	kU/L	1	Low levels of allergen specific IgE
0.70 - 3.49	kU/L	2	Moderate levels of allergen specific IgE
3.50 - 17.49	kU/L	3	High Levels of allergen specific IgE
17.50 - 49.99	kU/L	4	Very High levels of allergen specific IgE
50.00 - 100.00	kU/L	5	Very High levels of allergen specific IgE
> 100.00	kU/L	6	Extremely High levels of allergen specific IgE

Referral Location

Canada

Interface & Setup

HL7 Interface Codes

Order Code	Result Name	Result Codes	Units
LEPDES	Lepidoglyphus Destructor (d71) IgE, Serum

Test Version

Last Updated

2023-11-17