Islet Cell Antibody Screen; Islet Cell Antibody Titer
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Islet Cell Antibodies with Reflex Titer, Serum
Test ID: ICAB
Test
Method
Immunofluorescence Assay (IFA)
Report Includes
Specimens
Serum
Clinical Utility
Type 1 diabetes is characterized by lymphocytic cell infiltrate of the pancreatic islets. Measurement of GAD-65, ICA-512, and Insulin Antibody is a highly sensitive means to assess risk and predict onset of Type 1 diabetes. There is a correlation between the number of positive antibodies and the antibody titers versus the severity of the autoimmune process.
Test Location
Quest Diagnostics, California USA
Test Version
10-Feb-2025
Specimen
Specimens
Serum
Sample Volume
2.0 mL
Minimum Volume
0.5 mL
Collection & Handling
Handling Information
Store and send cold.
Additional Information
If Islet Cell Antibody Screen is positive, Islet Cell Antibody Titer will be performed at an additional fee.
Stability
| Ambient | 48 hours |
|---|---|
| Refrigerated | 14 days |
| Frozen | 6 months |
Rejection Criteria
| Hemolysis | Gross |
|---|---|
| Lipemia | Present |
| Other | Icteric |
Test Version
10-Feb-2025
Performance / Interpretation
Method
Immunofluorescence Assay (IFA)
Turnaround Time
13 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Islet Cell Antibody Screen | Qualitative Test |
|
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| Islet Cell Antibody Titer | JDF Units |
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Test Location
Quest Diagnostics, California USA
Test Version
10-Feb-2025
Interface / Setup
Test Version
10-Feb-2025