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Test ID: IGGSUB

Immunoglobulin G (IgG) Subclasses, Serum

Test Overview

Method

Turbidimetry

Analytical Platform

SPA Plus™

Result Included

IgG 1 Subclass; IgG 2 Subclass; IgG 3 Subclass; IgG 4 Subclass; Total IgG

Aliases/Synonyms

IgG Subclasses Panel

Specimen

Specimen Type

Serum

Containers

Collection Containers

Gold top (clot activator & gel)

Volume

Sample Volume

1 mL

Minimum Volume

0.5 mL

Collection & Handling

Handling Information

Store and send frozen.

Additional Information

Provide date of birth and gender. The report will not include reference ranges when age and gender are not provided.

Stability

Refrigerated	Frozen
3 days	6 months

Rejection Criteria

Criteria	Specification
Hemolysis	Present

Performance & Interpretation

Turnaround Time

7 days

Results

IgG 1 Subclass

g/L

0 - 2 y: 1.94 - 8.42
2 - 4 y: 3.15 - 9.45
4 - 6 y: 3.06 - 9.45
6 - 8 y: 2.88 - 9.18
8 - 10 y: 4.32 - 10.20
10 - 12 y: 4.23 - 10.60
12 - 14 y: 3.42 - 11.50
14 - 18 y: 3.15 - 8.55
≥18 y: 3.82 - 9.29

mg/L x 0.0100
IgG 2 Subclass

g/L

0 - 2 y: 0.23 - 3.00
2 - 4 y: 0.36 - 2.25
4 - 6 y: 0.61 - 3.45
6 - 8 y: 0.44 - 3.75
8 - 10 y: 0.72 - 4.30
10 - 12 y: 0.76 - 3.55
12 - 14 y: 1.00 - 4.55
14 - 18 y: 0.64 - 4.95
≥18 y: 2.42 - 7.00

mg/L x 0.0100
IgG 3 Subclass

g/L

0 - 2 y: 0.19 - 0.85
2 - 4 y: 0.17 - 0.68
4 - 6 y: 0.10 - 1.22
6 - 8 y: 0.16 - 0.85
8 - 10 y: 0.13 - 0.85
10 - 12 y: 0.17 - 1.73
12 - 14 y: 0.28 - 1.25
14 - 18 y: 0.23 - 1.96
≥18 y: 0.22 - 1.76

mg/L x 0.0100
IgG 4 Subclass

g/L

0 - 2y: 0.005 - 0.784
2 - 4 y: 0.010 - 0.537
4 - 6 y: 0.018 - 1.125
6 - 8 y: 0.004 - 0.992
8 - 10 y: 0.019 - 0.932
10 - 12 y: 0.016 - 1.150
12 - 14 y: 0.037 - 1.360
14 - 18 y: 0.110 - 1.570
≥18 y: 0.039 - 0.864

mg/L x 0.0100
Immunoglobulin G (IgG)

g/L

0 - 1 y: 2.3 - 14.1
1 - 4 y: 4.5 - 14.3
4 - 7 y: 5.0 - 14.6
7 - 10 y: 5.7 - 14.7
10 - 14 y: 7.0 - 15.5
14 - 20 y: 7.2 - 15.8
> 20 y: 6.1 - 16.2

mg/dL x 0.0100

Comment

Measured total IgG may be approximate but not exactly equal to the calculated sum of IgG subclasses as each antibody is measured independently and is subject to slightly different variations in assay performance. Measured Total IgG is assessed for acceptable variance from the sum of the individually measured IgG Subclasses.

Referral Location

Canada

Interface & Setup

HL7 Interface Codes

Order Code	Result Name	Result Codes	Units
IGGSUB	IgG1	28900	g/L
	IgG2	28902	g/L
	IgG3	28904	g/L
	IgG4	28906	g/L
	IgG	1621	g/L

Test Version

Last Updated

2025-03-11