Test Overview
Method
Liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Result Included
Imipramine; Desipramine; Imipramine + Desipramine
Specimen
Specimen Type
Avoid gel separator tubesSerum
Plasma (EDTA)
Volume
Sample Volume
3 mL
Specimen Comment
Avoid gel separator tubes.
Collection & Handling
Collection Instructions
Collect trough specimen (i.e. collected within 1 hours prior to next dose or at least 12 hours after last dose.)
Handling Information
Separate as soon as possible.
Stability
| Ambient | Refrigerated | Frozen |
|---|---|---|
| 5 days | 2 weeks | 6 months |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Specimen | Gel-separator tube |
Performance & Interpretation
Turnaround Time
7 days
Results
Name
Units
Reference Range
Conversion
-
Imipramineng/mLNo therapeutic range for Imipramine alone
-
Desipramineng/mLNo therapeutic range for Imipramine alone
-
Imipramine + Desipramineng/mLTherapeutic: 175 - 300
Toxic: > 300
Comment
(Effective 18-Oct-2022)
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| IMI | Imipramine | 7576 | ng/mL |
| Desipramine | 7577 | ng/mL | |
| Combined Metabolite | 7578 | ng/mL |
Test Version
Last Updated
2022-10-17