Rifadin; Rimactane
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Rifampin, Serum/Plasma
Test ID: RIFAM
Test
Aliases/Synonyms
Method
HPLC-UV
Report Includes
Rifampin Level
Specimens
Serum
Clinical Utility
Rifampin (RIF) is a first-line anti-tuberculosis (TB) and antimicrobial agent used in combination therapy for Mycobacterium tuberculosis infections, nontuberculous mycobacterial (NTM) infections, and certain bacterial infections such as Staphylococcus aureus endocarditis. Due to its complex pharmacokinetics and significant interpatient variability, therapeutic drug monitoring (TDM) is recommended to optimize efficacy while minimizing toxicity and drug resistance.
Test Version
19-Nov-2025
Specimen
Specimens
Serum
Collection Containers
Red top (no additive)
Sample Volume
2.0 mL
Minimum Volume
0.5 mL
Collection & Handling
Handling Information
Allow to clot for 30 minutes, separate serum from cells immediately by centrifugation and aliquot into a labeled polypropylene or similar plastic tube. Store and send frozen.
Stability
| Ambient | 6 hours |
|---|---|
| Frozen | > 6 hours |
Additional Stability Information
Freeze at -70C if possible, but at minimum -20C.
Rejection Criteria
| Specimen | Thawed samples for greater than 6 hours |
|---|
Test Version
19-Nov-2025
Performance / Interpretation
Method
HPLC-UV
Turnaround Time
14 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
|
||||
Test Version
19-Nov-2025
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| RIFAM | 62967Rifampin Level by HPLC | mcg/mL |
Test Version
19-Nov-2025