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Test ID: GRASSGX2

Grass Mix 2 (gx2) IgE, Serum

Orderable by Ontario ND

Test Overview

Clinical Utility

This assay provides a single qualitative (positive/negative) result only. It does not provide information on the amount of IgE specific for any of the component allergens within the mix panel.

In patients suffering from extrinsic asthma, hay fever or atopic eczema, symptoms develop after exposure to specific allergens. This immediate (atopic or anaphylactic) type of allergy is a function of a special type of serum antibodies belonging to the IgE class of immunoglobulins.

Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of symptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.

Analytical Platform

Phadia

Method Description

ImmunoCAP™ assays are based on binding of allergen-specific IgE antibodies in serum to allergen (extract or allergen molecule) coupled in excess to a solid phase. Bound IgE is subsequently detected with enzyme-labeled anti-human IgE, where the fluorescence intensity is proportional to the amount of allergen-specific IgE.

Result Included

Grass Mix 2 (gx2), IgE

Specimen

Specimen Type

Serum

Volume

Sample Volume

1 mL

Specimen Comment

Submit enough specimen for number of IgE tests ordered. Each test requires 50 µL and 2 mL is sufficient for 10-12 tests.

Collection & Handling

Handling Information

Store and send frozen.

Additional Information

Refer to the list of available IgE Allergen Tests.

Stability

Refrigerated Frozen
3 days 6 Months

Performance & Interpretation

Turnaround Time

10 days

Results

Name
Units
Reference Range
Conversion
  1. Grass Mix 2 (gx2), IgE
    KU/L
    Negative

    Comment

    This assay detects IgE antibodies to an allergen mix (Bahia g17, Bermuda g2, Johnson g10, Kentucky Blue (Meadow grass) g8, Rye g5, Timothy grass g6). This assay provides a single qualitative result only. It does not provide information on the amount of IgE specific for any of the allergens within the mix.

    Interpretation: Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of asymptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.

    Use caution when interpreting drug, venom and potential anaphylactic allergen results.

Referral Location

Canada

Interface & Setup

HL7 Interface Codes

Order Code Result Name Result Codes Units
GRASSGX2 IgE Grass Mix Gx2 31072

Test Version

Last Updated

2023-11-17