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Gentamicin – Trough, Serum

Test ID: GENTAT S

Test

Aliases/Synonyms

Aminoglycoside

Method

Enzyme Immunoassay

Platform

Roche cobas P6000

Report Includes

Gentamicin - Trough

Specimens

Serum

Test Location

St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8

Test Version

10-Dec-2019

Specimen

Specimens

Serum

Sample Volume

1 mL

Collection & Handling

Collection Instructions

Avoid gel-separator tubes.
Collect immediately before next dose. Wait until the third dose before collecting samples for therapeutic monitoring.

Handling Information

Store and send frozen.

Test Version

10-Dec-2019

Performance / Interpretation

Method

Enzyme Immunoassay

Platform

Roche cobas P6000

Turnaround Time

1 Day

Results

Name Units Reference Range Conversion Factor
Gentamicin - Trough mg/L
  • For traditional (conventional) dosing method:
     Pre-dose: <2.0 mg/L for adults and pediatrics
     Half-hour post-dose: 4.0 - 10.0 mg/L for adults ; 5.0 - 10.0 mg/L for pediatrics
    When used for synergy in the treatment of gram positive endocarditis in adults:
     Pre-dose: <1.0 mg/L
     Half-hour post-dose: 3.0 - 4.0 mg/L

    For extended interval (once daily) dosing method:
     Pre-dose <1.0 mg/L for adults
     8 - 12 hours post-dose for adults and use nomogram for interpretation;
     3 and 6 hours post-dose for pediatrics and use nomogram for interpretation.
Refer to guidelines for Aminoglycoside dosing at your institution.

Test Location

St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8

Test Version

10-Dec-2019

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
GENTAT S 63120Gentamicin, Before dose mg/L

Test Version

10-Dec-2019