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Back to Test Catalogue
Test ID: DS

Drug Screen, Serum

Test Overview

Method

Various

Method Description

Immunoassay: Acetaminophen, Barbiturates screen, Benzodiazepines screen, Tricyclic Antidepressants screen
Enzymatic/Colorimatric: Salicylate
GC-FID: Acetone, Ethanol, Isopropanol, Methanol

Result Included

Acetaminophen; Salicylate; Acetone; Isopropanol; Methanol; Barbiturates, Screen; Benzodiazepines, Screen; Tricyclic Antidepressants, Screen

Aliases/Synonyms

Acetaminophen; Acetone; Barbiturates, Screen; Benzodiazepines, Screen; Ethanol; Isopropanol; Methanol; Salicylate; Tricyclic Antidepressants, Screen

Specimen

Specimen Type

Serum
Avoid gel separator tubes.

Containers

Collection Containers

Red top (no additive)

Volume

Sample Volume

2 mL

Minimum Volume

2 mL

Specimen Comment

Avoid gel separator tubes.

Collection & Handling

Handling Information

Store and send frozen.

Additional Information

Provide list of prescribed drugs and/or reason for analysis e.g. monitoring, compliance or the name of the suspected drug.

Stability

Ambient Refrigerated Frozen
24 hours 7 days 28 dyas

Performance & Interpretation

Turnaround Time

2 days

Results

Name
Units
Reference Range
Conversion
  1. Acetaminophen
    µ mol/L
    0 - 66

    Comment

    Results > 66 µmol/L : Potentially toxic acetaminophen level depending on clinical context and time since last ingestion. Please refer to Rumack-Matthew nomogram if applicable (i.e., in suspected single acute ingestion)
    Results > 660 µmol/L: Suggests toxicity in patients presenting approx. 6 hours following single acute acetaminophen ingestion. Please refer to Rumack-Matthew nomogram.

  2. Acetone
    mmol/L
    Ketoacidosis: 1.7 - 12.0
  3. Barbiturates, screen
    Not Detected

    Comment

    Cut-off: 500 ng/mL

  4. Benzodiazepines, screen
    Not Detected

    Comment

    Cut-off: 100 ng/mL

  5. Ethanol
    mmol/L
    Toxic: > 39.0

    Impairment: 11.0 - 22.0

    CNS depression: > 22.0

    Fatalities:> 87.0

    Legal limit: 17.4
  6. Isopropanol
    mmol/L
    Toxic > 6.7
  7. Salicylate
    mmol/L
    Toxic: > 2.20

    Antipyretic/Analgesic: 0.15 - 0.72

    Anti-inflammatory: 1.00 - 2.00 mmol/L
  8. Tricyclic Antidepressants, screen
    Not Detected
    Cut-off: 300 ng/mL

Referral Location

Canada

Interface & Setup

HL7 Interface Codes

Order Code Result Name Result Codes Units
DS Tricyclics Scn 9368
Salicylate 9308 mmol/L
Barbiturates Scn 9313
Acetaminophen 9306 umol/L
Methanol 9357 mmol/L
Ethanol 9351 mmol/L
Isopropanol 9354 mmol/L
Acetone 9348 mmol/L
Benzodiazepine Scn 9371

Test Version

Last Updated

2023-03-17