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Dehydroepiandrosterone (DHEA) Unconjugated, Serum/Plasma

Test ID: DHEAQST SP
Test
Specimen
Performance / Interpretation
Interface / Setup

Test

Aliases/Synonyms

Unconjugated DHEA

Method

Chromatography/Mass Spectrometry

Specimens

Serum

Clinical Utility

DHEA is a weakly androgenic steroid that is useful when congenital adrenal hyperplasia is suspected. It is also useful in determining the source of androgens in hyperandrogenic conditions, such as polycystic ovarian syndrome and adrenal tumors.

Test Version

19-Nov-2025

Specimen

Specimens

Serum

Collection Containers

Preferred

Red top (no additive)

Acceptable

Lavender top (EDTA); Green top (lithium or sodium heparin)

Sample Volume

0.5 mL

Minimum Volume

0.3 mL

Patient Preparation

Overnight fasting is preferred.

Collection & Handling

Handling Information

Store and send frozen.

Stability

Ambient 6 hours
Refrigerated 72 hours
Frozen 90 days

Rejection Criteria

Hemolysis Gross
Specimen Gel separator tube

Test Version

19-Nov-2025

Performance / Interpretation

Method

Chromatography/Mass Spectrometry

Turnaround Time

10 days

Results

Name Units Reference Range Conversion Factor
DHEA, UNCONJUGATED ng/dL
  • Adult Males: 147 - 1760
    Females:
    Pre-Menopausal
    Mid Follicular: 385 - 1143
    Surge: 345 - 2030
    Mid Luteal: 414 - 1295
    Post-Menopausal: 77 - 851
    Pediatric
    1 - 11 months: ≤ 327
    1 year: ≤ 269
    2 years: ≤ 244
    3 years: ≤ 253
    4 years: ≤ 297
    5 years: ≤ 376
    6 years: ≤ 487
    7 years: ≤ 616
    8 years: 34 -744
    9 years: 45 - 854
    10 years: 56 - 950
    11 years: 67 - 1041
    12 years: 78 - 1120
    13 years: 86 - 1176
    14 years: 90 - 1207
    15 years: 95 - 1241
    16 years: 103 - 1294
    17 years: 113 - 1360

Test Version

19-Nov-2025

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
DHEAQST SP 65264DHEA, UNCONJUGATED ng/dL

Test Version

19-Nov-2025