Clozaril
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Clozapine and Norclozapine, Plasma
Test ID: CLOZA
Test
Aliases/Synonyms
Method
LC-MSD
Report Includes
Clozapine; Norclozapine
Specimens
Avoid gel separator tubes; Plasma (EDTA); Plasma (Li Heparin); Serum
Clinical Utility
Toxic effects are centrally mediated (CNS) and concentration dependent.
Hematological effects, agranulocytosis, are concentration independent.
Test Location
London Health Sciences Centre, 339 Windermere Road, London ON N6A 5A5
Test Version
15-Jan-2024
Specimen
Specimens
Avoid gel separator tubes; Plasma (EDTA); Plasma (Li Heparin); Serum
Collection Containers
Preferred
Plasma (EDTA lavender top)
Acceptable
Plasma (green top Li Heparin); Serum (red top)
Sample Volume
1 mL
Minimum Volume
0.5 mL
Specimen Comment
Avoid gel separator tubes.
Collection & Handling
Handling Information
Store and send frozen.
Test Version
15-Jan-2024
Performance / Interpretation
Method
LC-MSD
Turnaround Time
7 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Clozapine | nmol/L |
|
µg/L x 3.06 | |
| Norclozapine | nmol/L |
|
µg/L x 3.19 | |
Test Location
London Health Sciences Centre, 339 Windermere Road, London ON N6A 5A5
Test Version
15-Jan-2024
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| CLOZA | 20707Clozapine,S | nmol/L |
| 20708Norclozapine,S | nmol/L |
Test Version
15-Jan-2024