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C1 Esterase Inhibitor – Functional, Plasma

Test ID: C1EFUN

Test

Aliases/Synonyms

C1 Inhibitor Functional

Method

Chromogenic

Report Includes

C1 Esterase Inhibitor - Functional

Specimens

Plasma (Citrate)

Test Location

Laboratory Reference Centre, 237 Barton Street E, Hamilton ON L8L 2X2

Test Version

21-Mar-2023

Specimen

Specimens

Plasma (Citrate)

Collection Containers

Blue top (3.2% buffered citrate)

Sample Volume

1 mL

Collection & Handling

Collection Instructions

Separate plasma within 4 hours of collection.

Handling Information

Prepare platelet-poor plasma specimen and freeze immediately. Store and send frozen.

Stability

Ambient 4 hours
Frozen > 4 hours at -70°C

Additional Stability Information

If the specimen thaws, it is unsuitable for analysis. This assay is very sensitive to sample handling and storage conditions.

Rejection Criteria

Specimen Not frozen

Test Version

21-Mar-2023

Performance / Interpretation

Method

Chromogenic

Turnaround Time

14 days

Results

Name Units Reference Range Conversion Factor
C1 Esterase Inhibitor - Functional U/mL
  • 0.75 - 1.59
For assessment of angioedema correlate with other clinical features and with the results of quantitative levels of both C1 inhibitor protein and C4. This assay is very sensitive to sample handling and storage conditions. A repeat test (additional billing) with a fresh sample is recommended for results with borderline low/abnormal functional activity (0.69 - 0.74 U/mL).

Test Location

Laboratory Reference Centre, 237 Barton Street E, Hamilton ON L8L 2X2

Test Version

21-Mar-2023

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
C1EFUN 62115C1-INHIBITOR U/mL

Test Version

21-Mar-2023