Systemic Sclerosis (Scleroderma, nucleoli) Profile, Serum
Test Overview
Method
Immunoblot
Analytical Platform
Euroimmun EUROLINE immunoblot on EUROBlotMaster and evaluated on EUROLineScan
Result Included
Anti Scl-70 Ab (Anti Topoisomerase I antibody); Anti Centromere protein A Ab; Anti Centromere protein B Ab; Anti RP11 Ab (Anti RNA polymerase III (POLR3K) antibody); Anti RP155 Ab (Anti RNA polymerase III (POLR3A) antibody); Anti Fibrillarin (U3-RNP) Ab; Anti NOR90 Ab(Anti Nucleolus-organizing regions 90 kDa antigen antibody); Anti Th/To Ab; Anti PM-Scl 100 Ab (Anti PM/Scl Complex (100 kDa) antibody); Anti PM-Scl 75 Ab (Anti PM/Scl Complex (75 kDa) antibody); Anti Ku Ab; Anti PDGF Ab (Anti Platelet-derived growth factor receptor antibody); Anti Ro52 (TRIM21) Ab
Specimen
Specimen Type
SerumContainers
Collection Containers
Gold top (clot activator & gel)
Volume
Sample Volume
0.5 mL
Minimum Volume
0.3 mL
Collection & Handling
Collection Instructions
Separate as soon as possible. Store and send frozen.
Stability
| Refrigerated | Frozen |
|---|---|
| 14 days | 60 days |
Performance & Interpretation
Turnaround Time
14 days
Results
-
Anti Scl-70 AbNegative
-
Anti Centromere protein A AbNegative
-
Anti Centromere protein B AbNegative
-
Anti RP11 AbNegative
-
Anti RP155 AbNegative
-
Anti Fibrillarin (U3-RNP) AbNegative
-
Anti NOR90 AbNegative
-
Anti Th/To AbNegative
-
Anti PM-Scl 100 AbNegative
-
Anti PM-Scl 75 AbNegative
-
Anti Ku AbNegative
-
Anti PDGF AbNegative
-
Anti Ro52 (TRIM21) AbNegative
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| SSNAB S | Anti-Scl-70 antibody | 63584 | |
| Anti-Centromere protein A antibody | 63585 | ||
| Anti-Centromere protein B antibody | 63586 | ||
| Anti-RP11 antibody | 63614 | ||
| Anti-RP155 antibody | 63615 | ||
| Anti-Fibrillarin (U3-RNP) antibody | 63616 | ||
| Anti-NOR90 antibody | 63617 | ||
| Anti-Th/To antibody | 63618 | ||
| Anti-PM-Scl 100 antibody | 62081 | ||
| Anti-PM-Scl 75 antibody | 62082 | ||
| Anti-Ku antibody | 62080 | ||
| Anti-PDGF antibody | 63622 | ||
| Anti-Ro52 (TRIM21) antibody | 62089 | ||
| Interpretation | 63624 |
Test Version
Last Updated
2025-02-12