Animal Mix (ex2) IgE
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Animal Mix (ex2) IgE, Serum
Test ID: MIXEX2
Orderable by Ontario ND
Test
Method
ImmunoCAP™
Method Description
ImmunoCAP™ assays are based on binding of allergen-specific IgE antibodies in serum to allergen (extract or allergen molecule) coupled in excess to a solid phase. Bound IgE is subsequently detected with enzyme-labeled anti-human IgE, where the fluorescence intensity is proportional to the amount of allergen-specific IgE.
Platform
Phadia
Report Includes
Specimens
Serum
Clinical Utility
This assay provides a single qualitative (positive/negative) result only. It does not provide information on the amount of IgE specific for any of the component allergens within the mix panel.
In patients suffering from extrinsic asthma, hay fever or atopic eczema, symptoms develop after exposure to specific allergens. This immediate (atopic or anaphylactic) type of allergy is a function of a special type of serum antibodies belonging to the IgE class of immunoglobulins.
Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of symptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.
Test Location
Hamilton General Hospital, 237 Barton St E, Hamilton ON L8L 2X2
Test Version
17-Nov-2023
Specimen
Specimens
Serum
Sample Volume
1 mL
Specimen Comment
Submit enough specimen for number of IgE tests ordered. Each test requires 50 µL and 2 mL is sufficient for 10-12 tests.
Collection & Handling
Handling Information
Store and send frozen.
Additional Information
Refer to the list of available IgE Allergen Tests.
Stability
| Refrigerated | 3 days |
|---|---|
| Frozen | 6 Months |
Test Version
17-Nov-2023
Performance / Interpretation
Method
ImmunoCAP™
Method Description
ImmunoCAP™ assays are based on binding of allergen-specific IgE antibodies in serum to allergen (extract or allergen molecule) coupled in excess to a solid phase. Bound IgE is subsequently detected with enzyme-labeled anti-human IgE, where the fluorescence intensity is proportional to the amount of allergen-specific IgE.
Platform
Phadia
Turnaround Time
10 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Animal Mix (ex2), IgE | KU/L |
|
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This assay detects IgE antibodies to an allergen mix (Cat Dander e1, Dog Dander e5, Guinea pig epithelium e6, Rat e87, Mouse e88). This assay provides a single qualitative result only. It does not provide information on the amount of IgE specific for any of the allergens within the mix. Interpretation: Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of asymptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens. Use caution when interpreting drug, venom and potential anaphylactic allergen results. |
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Test Location
Hamilton General Hospital, 237 Barton St E, Hamilton ON L8L 2X2
Test Version
17-Nov-2023
Interface / Setup
Test Version
17-Nov-2023