SRA
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Serotonin Release Assay (HIT), Serum and Plasma
Test ID: SRAHIT PS
Test
Aliases/Synonyms
Method
Platelet function assay
Report Includes
Serotonin Release Assay
Specimens
Plasma and Serum
Clinical Utility
This is a research test and the results must be interpreted in the clinical context.
(1. Kelton JG., Heparin-induced thrombocytopenia: an overview. Blood reviews. 2002:16; 77-80.
2. Warkentin TE, Sheepard J-A., Testing for heparin-induced thrombocytopenia antibodies. Transfusion Medicine reviews. 2006:20;259-272)
Test Location
McMaster Platelet Immunology Lab, 1200 Main Street West, Hamilton ON L8N 3Z5
Test Version
6-Sep-2023
Specimen
Specimens
Plasma and Serum
Collection Containers
Blue top (3.2% buffered citrate); Gold Top (gel & clot activator)
Sample Volume
2 mL (each)
Collection & Handling
Collection Instructions
Collect serum and plasma.
Handling Information
Separate as soon as possible. Prepare two aliquots (2 mL of serum AND 2 mL of plasma). Indicate specimen type clearly on each specimen vial. Freeze immediately. Store and send frozen.
Stability
| Frozen | 1 year |
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Additional Stability Information
If the specimen thaws, it is unsuitable for analysis.
Rejection Criteria
| Specimen | Not frozen |
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Test Version
6-Sep-2023
Performance / Interpretation
Method
Platelet function assay
Turnaround Time
6 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Serotonin Release Assay (HIT) | Qualitative test |
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This is a research test and the results must be interpreted in the clinical context.
(1. Kelton JG., Heparin-induced thrombocytopenia: an overview. Blood reviews. 2002:16; 77-80. 2. Warkentin TE, Sheepard J-A., Testing for heparin-induced thrombocytopenia antibodies. Transfusion Medicine reviews. 2006:20;259-272) |
||||
Test Location
McMaster Platelet Immunology Lab, 1200 Main Street West, Hamilton ON L8N 3Z5
Test Version
6-Sep-2023
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| SRAHIT PS | 65196SEROTONIN RELEASE ASSAY (SRA) |
Test Version
6-Sep-2023