Serotonin Release Assay (HIT), Serum and Plasma
Test Overview
Clinical Utility
This is a research test and the results must be interpreted in the clinical context.
(1. Kelton JG., Heparin-induced thrombocytopenia: an overview. Blood reviews. 2002:16; 77-80.
2. Warkentin TE, Sheepard J-A., Testing for heparin-induced thrombocytopenia antibodies. Transfusion Medicine reviews. 2006:20;259-272)
Method
Platelet function assay
Result Included
Serotonin Release Assay
Aliases/Synonyms
SRA
Specimen
Specimen Type
Plasma and SerumContainers
Collection Containers
Blue top (3.2% buffered citrate); Gold Top (gel & clot activator)
Volume
Sample Volume
2 mL (each)
Collection & Handling
Collection Instructions
Collect serum and plasma.
Handling Information
Separate as soon as possible. Prepare two aliquots (2 mL of serum AND 2 mL of plasma). Indicate specimen type clearly on each specimen vial. Freeze immediately. Store and send frozen.
Stability
| Frozen |
|---|
| 1 year |
If the specimen thaws, it is unsuitable for analysis.
Rejection Criteria
| Criteria | Specification |
|---|---|
| Specimen | Not frozen |
Performance & Interpretation
Turnaround Time
6 days
Results
-
Serotonin Release Assay (HIT)Qualitative testNegative
Comment
This is a research test and the results must be interpreted in the clinical context.
(1. Kelton JG., Heparin-induced thrombocytopenia: an overview. Blood reviews. 2002:16; 77-80.
2. Warkentin TE, Sheepard J-A., Testing for heparin-induced thrombocytopenia antibodies. Transfusion Medicine reviews. 2006:20;259-272)
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| SRAHIT PS | SEROTONIN RELEASE ASSAY (SRA) | 65196 |
Test Version
Last Updated
2023-09-06