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Serotonin Release Assay (HIT), Serum and Plasma

Test ID: SRAHIT PS

Test

Aliases/Synonyms

SRA

Method

Platelet function assay

Report Includes

Serotonin Release Assay

Specimens

Plasma and Serum

Clinical Utility

This is a research test and the results must be interpreted in the clinical context.
(1. Kelton JG., Heparin-induced thrombocytopenia: an overview. Blood reviews. 2002:16; 77-80.
2. Warkentin TE, Sheepard J-A., Testing for heparin-induced thrombocytopenia antibodies. Transfusion Medicine reviews. 2006:20;259-272)

Test Location

McMaster Platelet Immunology Lab, 1200 Main Street West, Hamilton ON L8N 3Z5

Test Version

6-Sep-2023

Specimen

Specimens

Plasma and Serum

Collection Containers

Blue top (3.2% buffered citrate); Gold Top (gel & clot activator)

Sample Volume

2 mL (each)

Collection & Handling

Collection Instructions

Collect serum and plasma.

Handling Information

Separate as soon as possible. Prepare two aliquots (2 mL of serum AND 2 mL of plasma). Indicate specimen type clearly on each specimen vial. Freeze immediately. Store and send frozen.

Stability

Frozen 1 year

Additional Stability Information

If the specimen thaws, it is unsuitable for analysis.

Rejection Criteria

Specimen Not frozen

Test Version

6-Sep-2023

Performance / Interpretation

Method

Platelet function assay

Turnaround Time

6 days

Results

Name Units Reference Range Conversion Factor
Serotonin Release Assay (HIT) Qualitative test
  • Negative
This is a research test and the results must be interpreted in the clinical context.
(1. Kelton JG., Heparin-induced thrombocytopenia: an overview. Blood reviews. 2002:16; 77-80.
2. Warkentin TE, Sheepard J-A., Testing for heparin-induced thrombocytopenia antibodies. Transfusion Medicine reviews. 2006:20;259-272)

Test Location

McMaster Platelet Immunology Lab, 1200 Main Street West, Hamilton ON L8N 3Z5

Test Version

6-Sep-2023

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
SRAHIT PS 65196SEROTONIN RELEASE ASSAY (SRA)

Test Version

6-Sep-2023