Ntelopeptide
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Collagen Cross-Linked N-Telopeptide (NTx), 24 hr Urine
Test ID: NTELOPEP U
Test
Aliases/Synonyms
Method
Chemiluminescence
Report Includes
N-Telopeptide; Creatinine
Specimens
Urine (24hr)
Clinical Utility
NTx is useful to assess bone resorption in patients with metabolic bone disease and monitor therapy to slow or halt osteoporotic bone loss. A decline of 30% or more of NTx over a six-month period suggests effective therapy.
Test Location
Quest Diagnostics, California USA
Test Version
1-Sep-2023
Specimen
Specimens
Urine (24hr)
Collection Containers
Sterile Container
Sample Volume
2 mL
Minimum Volume
1 mL
Collection & Handling
Collection Instructions
Do not include first morning specimen; collect all subsequent voidings. The last sample collected should be the first morning specimen voided the following morning at the same time as the previous morning’s first voiding.
Handling Information
Specify 24-hour total volume on aliquot container and test requisition. Store and send frozen.
Stability
| Ambient | 3 days |
|---|---|
| Refrigerated | 5 days |
| Frozen | 30 days |
Rejection Criteria
| Specimen | Preserved |
|---|
Test Version
1-Sep-2023
Performance / Interpretation
Method
Chemiluminescence
Turnaround Time
6 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| N-Telopeptide, 24 hr Urine | nM BCE/mM creat |
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Results are primarily used for monitoring the response to therapy. A value within the premenopausal reference range does not rule out osteoporosis nor the need for therapy.
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| Creatinine, 24-Hour Urine | g/24 h |
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Test Location
Quest Diagnostics, California USA
Test Version
1-Sep-2023
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| NTELOPEP U | 64479Total Volume | mL |
| 65193N-Telopeptide (NTx), 24 U | nM BCE/mM creat | |
| 65194Creatinine, 24-hour Urine | MG/24 hr |
Test Version
1-Sep-2023