Remicade; Inflectra; Renflexis
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Infliximab with Reflex Antibodies, Serum
Test ID: INFLIXSPH S
Test
Aliases/Synonyms
Method
Various
Method Description
Infliximab Quantitation: Mass Spectrometry
Infliximab Antibodies: semi-quantitative ELISA (Immunodiagnostik)
Report Includes
Infliximab; Infliximab Antibodies
Specimens
Serum
Clinical Utility
Infliximab Antibodies will only be tested (and billed) when the measured Infliximab concentration is subtherapeutic (Infliximab ≤ 5 µg/mL).
Test Location
St. Paul's Hospital Laboratory, 1081 Burrard St, Vancouver, BC V6Z 1Y6
Test Version
18-Oct-2023
Specimen
Specimens
Serum
Collection Containers
Preferred
Red top (no additive)
Acceptable
Gold Top (clot activator and gel)
Sample Volume
3 mL
Minimum Volume
2 mL
Collection & Handling
Collection Instructions
Collect trough specimen immediately prior to the next infusion.
Handling Information
Please indicate date/time of last infusion. Store and send cold or frozen.
Additional Information
Date/time of last infusion is requested to facilitate appropriate interpretation and to assist the test provider in troubleshooting unusual findings and in support of appropriate utilization (e.g., collection at true trough).
Stability
| Ambient | 7 days |
|---|---|
| Refrigerated | 7 days |
| Frozen | 28 days |
Test Version
18-Oct-2023
Performance / Interpretation
Method
Various
Method Description
Infliximab Quantitation: Mass Spectrometry
Infliximab Antibodies: semi-quantitative ELISA (Immunodiagnostik)
Turnaround Time
9 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Infliximab | µg/mL |
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When infliximab trough concentration is greater than 5.0 µg/mL, clinically relevant antibodies to infliximab are unlikely and reflex antibody testing is not performed.
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| Infliximab Antibodies |
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Interpretation
1+: Antibodies to infliximab detected, clinical significance uncertain. 2+: Antibodies to infliximab detected at significant concentrations. 3+: Antibodies to infliximab detected at significant concentrations. |
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Test Location
St. Paul's Hospital Laboratory, 1081 Burrard St, Vancouver, BC V6Z 1Y6
Test Version
18-Oct-2023
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| Multiple | 0HL7 codes |
Test Version
18-Oct-2023